When most people think about weight loss, they focus on how quickly the number on the scale goes down. But one of the most important factors in a healthy and sustainable weight-loss journey, especially on a GLP-1, is muscle health.
At Shed, we view weight loss as more than calorie reduction. We see it as a metabolic rebuilding process, where preserving lean muscle plays a central role in long-term success.
Why muscle health matters during GLP-1 weight loss
GLP-1 medications can be incredibly supportive for appetite regulation, portion control, and reducing food noise. For many individuals, this creates the mental and emotional space needed to finally focus on overall health.
At the same time, GLP-1s often lead to:
- Lower overall calorie intake
- Smaller portions
- Reduced hunger cues
- Quick weight loss initially
While these effects can be beneficial, they also increase the importance of intentional nutrition and movement.
When calories and protein drop too low, the body may lose both fat and lean mass. Preserving muscle ensures that weight loss is not only visible on the scale, but functional, sustainable, and supportive of long-term health.
Muscle plays a key role in:
- Metabolic health and insulin sensitivity
- Physical function and mobility
- Bone density and injury prevention
- Long-term weight maintenance
- Energy levels and resilience
The risk of losing lean mass while on a GLP-1
Losing weight isn’t always the same as getting healthier.
Rapid or aggressive weight loss, whether from extreme dieting, under-fueling, or inconsistent movement, can increase the risk of losing lean tissue alongside fat.
This matters because lean mass:
- Supports resting metabolic rate
- Helps regulate blood sugar
- Protects against fatigue and weakness
- Improves recovery from illness or stress
- Supports immune function
Without adequate protein, sufficient overall energy intake, resistance-based movement, and proper recovery, the body may begin using muscle tissue as an energy source. Over time, this can make progress harder to sustain and increase the likelihood of weight regain.

How exercise supports muscle health
It’s not about intensity; it’s about consistency.
Exercise is one of the most powerful tools for preserving muscle, but it doesn’t need to be extreme to be effective. The body responds best to:
- Regular movement
- Progressive resistance
- Adequate recovery
- Sufficient protein and targeted nutrition
- Proper hydration
This means that strength training, resistance bands, bodyweight exercises, walking, and even chair-based workouts all support muscle health when done consistently.
Even 20 minutes of intentional movement 2–3 days per week can help preserve lean mass during weight loss.
At Shed, members have access to:
- Guided workout videos
- Walking programs
- Resistance band training
- Chair workouts and chair Pilates
- 3-day and 5-day weekly plans
- 4-week fitness challenges
The goal is not to punish the body, but to signal to it that muscle is needed and valuable. Visit our Community (login required) for more resources and support.
Supporting recovery and growth: The role of sermorelin
Sermorelin is a growth hormone–stimulating hormone (GHSH) analog. Rather than supplying growth hormone directly, it works by signaling the body to stimulate its own natural production.
Growth hormone plays a role in:
- Tissue repair and recovery
- Muscle protein synthesis
- Sleep quality
- Body composition regulation
Sermorelin is often explored by individuals interested in supporting recovery from training, preserving lean muscle mass, improving sleep quality, and enhancining overall vitality.
In addition, it is commonly considered by adults who notice slower recovery, lower energy, or changes in body composition over time.
As with any prescription therapy, Sermorelin works best when paired with:
- Adequate protein intake
- Consistent movement
- Quality sleep
- Proper hydration and nutrition
Sermorelin is not a replacement for lifestyle habits, but rather a supportive tool within a comprehensive health plan. A licensed healthcare provider can help determine if Sermorelin is appropriate for your needs.
Nutrition matters: Protein and hydration
Muscle cannot be maintained without the right building blocks.
The Shed Metabolic Foundation Plan and endless recipes such as our High-Protein Recipe packet are all designed to support lean muscle mass while guiding members through sustainable nutrition practices for repair, recovery, and long-term health.
Protein provides the amino acids needed for:
- Muscle repair
- Muscle growth
- Enzyme and hormone production
- Immune function
A general guideline for individuals on GLP-1s is 1.2–1.6 grams of protein per kilogram of body weight (or goal weight) per day.
Hydration is also important for muscle health. It supports:
- Muscle contraction
- Nutrient delivery
- Exercise performance
- Recovery and circulation
Shed’s Clear Protein + Hydration was developed to make both simple:
- High-quality protein in an easy-to-digest form
- Electrolytes to support hydration
- A practical option for low-appetite phases
It’s especially helpful for:
- Post-workout recovery
- Busy schedules
- Individuals who struggle to eat enough protein
- Those who dislike heavy protein shakes

Movement for every starting point
At Shed, we believe movement should be accessible, not intimidating.
Not everyone starts in the same place, and that’s okay.
Our fitness ecosystem supports:
- Beginners and advanced movers
- At-home and gym-based routines
- Joint-friendly and low-impact options
- Individuals starting from a chair
Whether you’re returning to movement after a long break or training regularly in the gym, there is a path forward, no matter your limitations or time constraints. Visit our Health Coaching page to find out how to get started from where you're at.
Muscle health is not just for athletes. It’s also important for aging adults, individuals with chronic conditions, people on GLP-1s, and anyone who wants to feel stronger. In other words, muscle health should be a priority for everyone.
The bigger picture: Muscle as a longevity tool
Preserving muscle is one of the strongest predictors of:
- Independence with age
- Lower risk of falls
- Better metabolic health
- Higher quality of life
At Shed, exercise is not framed as punishment or compensation for eating. It is framed as a form of self-support.
When muscle is protected, the body becomes more resilient, more adaptable, more metabolically flexible, and better-equipped for long-term success.
Final thoughts
Weight loss should never come at the cost of strength, function, or health.
By combining accessible movement, adequate protein and hydration, supportive tools like Sermorelin, and education and community, Shed helps individuals lose weight while becoming stronger, not just smaller.
Muscle is not something to fear during weight loss.
It is something to protect, nourish, and build—for life.
Ready to get started? Visit tryshed.com today to learn more about how Shed can help you in your health journey.
FAQs
Does GLP-1 weight loss always cause muscle loss?
Not necessarily, but it can happen if muscle-preserving habits aren’t in place. Intentional protein intake, resistance training, and recovery support can help improve the ratio of fat loss to muscle loss.
Can you build muscle while losing weight on a GLP-1?
Yes, especially when paired with structured strength training and adequate protein. Studies have shown that some individuals maintained or even increased lean tissue while losing fat mass when combining GLP-1 treatment with exercise and targeted nutrition.
If I’m eating less overall, will my body automatically burn muscle?
Not automatically, but risk increases if calories and protein drop too low and movement is inconsistent. During rapid weight loss, the body may use muscle tissue for energy if it isn’t receiving enough nutritional and mechanical signals to keep it.
Why does muscle matter for metabolism and long-term weight maintenance?
Lean muscle mass supports resting metabolic rate, insulin sensitivity, and functional strength. Losing too much muscle can make long-term weight maintenance harder and may reduce energy levels and resilience.
What are early signs I might be losing muscle during weight loss?
Possible signs include noticeable strength loss, increased fatigue during normal activity, slower workout recovery, and feeling weaker despite scale weight dropping. Body composition tracking (not just scale weight) can help catch this early.
This blog is for educational purposes only and is not intended to replace medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting or changing any medication, supplement, or exercise program. Individual needs and responses may vary.




