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*In clinical trials of Wegovy® (FDA-approved semaglutide), participants achieved an average weight loss of approximately 15% over 68 weeks, with some participants achieving up to 20% with continued treatment and adherence, when combined with diet and exercise. This compares to approximately 2–3% weight loss with diet and exercise alone.

Buy Naltrexone + Bupropion Online

Starting at $149/ month + $99/month Shed Membership
Lose 14-15% of your body weight*
FDA-approved GLP-1. Now in a pen and a pill.
Insurance or cash-pay options
100% online, provider-led care

Naltrexone + Bupropion is a non-stimulant combination that can help support your weight management journey by working on brain pathways related to cravings, reward, and appetite regulation. This combination is non-habit-forming and may promote more mindful eating habits, especially if emotional or reward-driven eating has been a challenge. When used alongside healthy lifestyle changes, including diet and physical activity, it may contribute to sustainable weight loss over time.

In clinical trials of Wegovy® (FDA-approved semaglutide), participants achieved an average weight loss of approximately 15% over 68 weeks, with some participants achieving up to 20% with continued treatment and adherence, when combined with diet and exercise. This compares to approximately 2–3% weight loss with diet and exercise alone.
FAQ

What is Wegovy®?

Wegovy® (semaglutide) is an FDA-approved prescription medication used for chronic weight management in adults with obesity or excess weight. It belongs to a class of medications called GLP-1 receptor agonists.

Wegovy® works by mimicking a natural hormone in your body that helps regulate appetite and blood sugar, which can support reduced food intake and healthier eating patterns when combined with lifestyle changes.

FAQ

How effective is Wegovy® for weight loss?

Wegovy® has been clinically studied for weight management. In clinical trials, adults who used Wegovy® alongside diet and lifestyle changes lost an average of 14–15% of their body weight over one year.*

Individual results vary based on factors such as dosage, adherence, lifestyle habits, and overall health.

FAQ

What is the Wegovy® pill, and how is it different from the Wegovy® pen?

Both the Wegovy® pill and the Wegovy® pen contain the same active ingredient, semaglutide, and are FDA-approved for weight management. The main difference is how and how often they’re taken.

Similarities:

  • Both are FDA-approved Wegovy® formulations
  • Both use semaglutide as the active ingredient
  • Both follow a gradual dose-increase schedule determined by a provider
  • Side effects are generally similar and can be managed with provider support

Differences:

  • Wegovy® pen: Taken as a once-weekly injection
  • Wegovy® pill: Taken orally once per day

Your Shed provider will help determine which option may be appropriate based on your health history, preferences, and treatment goals.

FAQ

What’s the difference between Ozempic® and Wegovy®?

Both medications contain semaglutide, but they are FDA-approved for different uses.

  • Ozempic® is approved to treat type 2 diabetes
  • Wegovy® is specifically approved for chronic weight management

In some cases, providers may prescribe Ozempic® off-label for weight management when appropriate, but Wegovy® is the formulation designed and approved for weight loss.

Health

What is Wegovy®?

Health

How effective is Wegovy® for weight loss?

Health

What is the Wegovy® pill, and how is it different from the Wegovy® pen?

Health

What’s the difference between Ozempic® and Wegovy®?

Meet the Wegovy® Pill

Lose
14-15%
of your body weight*
A new, FDA-approved way to take Wegovy®, no injections required.

Wegovy® is now available as a once-daily pill, offering a needle-free option for people who prefer oral medication. Like the Wegovy® pen, the pill contains semaglutide and is FDA-approved for chronic weight management.

This new delivery method gives patients more flexibility in how they take Wegovy®, while still receiving provider-guided care through Shed.

Lose
14-15%
of your body weight*

*In clinical trials of Wegovy® (FDA-approved semaglutide), participants achieved an average weight loss of approximately 15% over 68 weeks, with some participants achieving up to 20% with continued treatment and adherence, when combined with diet and exercise. This compares to approximately 2–3% weight loss with diet and exercise alone.

Two ways to take Wegovy®

Same active ingredient. Two FDA-approved delivery options, guided by your provider.
Feature
Medication Type
FDA-approved
Active ingredient
Average weight loss
Price
Wegovy® Pen
Once weekly
Yes
Semaglutide
15% in a year*
Starts at $199






Wegovy® Pill
Once daily
Yes
Semaglutide
14% in a year*
Starts at $149

Two ways to take Wegovy®

Same active ingredient. Two FDA-approved delivery options, guided by your provider.
Pen
Wegovy® Pen
Medication Type
Once-weekly injection
FDA-approved
Yes
Active ingredient
Semaglutide
Average weight loss
15% in a year*
Insurance or cash-pay
Either
Price
Starts at $199
Pill
Wegovy® Pill
Medication Type
Once-daily pill
FDA-approved
Yes
Active ingredient
Semaglutide
Average weight loss
14% in a year*
Insurance or cash-pay
Either
Price
Starts at $149

Join 100,000+ members who’ve reached their weight-loss goals with Shed

Before
After
Dani
"My kids have told me multiple times I'm the funnest mom ever lately, I have more energy. I've been getting more done."
Before
After
Bjorn
“The journey is tough and challenging, but fruitful. Knowing your body's capability and constantly challenging yourself I find is the key. Consistency is the key.”
Before
After
Sue
"I am currently at 144 lbs and I feel the best I have ever felt. I am hoping to continue in my fitness and weight-loss journey."
Before
After
Dawn
I have [lost] 53 pounds since October so far on the [GLP-1] injection. I absolutely love this tool. Not only does it curb, appetite, and help with food noise, my pain from inflammation is gone. I am so glad I found this company.”
Lost 53 lbs.

Your simple 4-step weight-loss plan

Step 1

Take a 5-minute quiz

Answer a few questions about your health history and goals, so we can match you with the right program.
Step 2

Provider Review

A medical provider will look over your answers and determine if you’re a good fit.
Step 3

Medications shipped to your home

If prescribed, your prescription will be delivered to your doorstep with clear instructions based on your prescribed format (injection or pill).
Step 4

Ongoing support

Get access to Shed Health Coaching, unlimited provider follow-ups, step-by-step health courses, and more.*

Start your weight-loss journey with Wegovy®

Start your weight-loss journey with Wegovy®

Supports healthy metabolic function*
Slows digestion*
Can reduce appetite*
Supports weight management*
FDA approved
Clinically studied
Easy to use
*This information is for educational purposes only and is not a substitute for professional medical advice. Please consult your healthcare provider before starting or changing any medication or treatment. Results may vary.
Shed Team

With you from day one

To ensure you get the results you’re working toward, you'll be assigned a team of experts to be with you at every step of your evolution.
Neely Wood (RN)
Your nurse is here to support your care, answer questions, and help you feel confident throughout your journey. They work closely with your provider to ensure you have what you need.
Noah Swendson
Your Member Success Manager is your go-to support person throughout your journey. They’ll check in regularly to answer questions and make sure you’re fully supported every step of the way.
Dr. Asad Niazi (MD)
Your provider will prescribe the best medication for your needs and adjust it as needed. You’ll have free follow-up appointments to make sure you’re feeling great and getting expert, personalized care.
Pardise Mossalman (CHC)
Your Health Coach will guide you in building healthy habits that complement your medication. Together, you’ll create sustainable changes to help you reach your goals.
Roseanne Schnell (RD)
Our expert coaches and nutritionists have created online resources to help you make lasting lifestyle changes. Whether you're learning about nutrition, movement, or mindset, everything is designed to support your success.
Shed FAQs

Questions? We’ve got answers.

Health

What is Wegovy®?

Wegovy® (semaglutide) is an FDA-approved prescription medication used for chronic weight management in adults with obesity or excess weight. It belongs to a class of medications called GLP-1 receptor agonists.

Wegovy® works by mimicking a natural hormone in your body that helps regulate appetite and blood sugar, which can support reduced food intake and healthier eating patterns when combined with lifestyle changes.

Health

How effective is Wegovy® for weight loss?

Wegovy® has been clinically studied for weight management. In clinical trials, adults who used Wegovy® alongside diet and lifestyle changes lost an average of 14–15% of their body weight over one year.*

Individual results vary based on factors such as dosage, adherence, lifestyle habits, and overall health.

Health

What is the Wegovy® pill, and how is it different from the Wegovy® pen?

Both the Wegovy® pill and the Wegovy® pen contain the same active ingredient, semaglutide, and are FDA-approved for weight management. The main difference is how and how often they’re taken.Similarities:

  • Both are FDA-approved Wegovy® formulations
  • Both use semaglutide as the active ingredient
  • Both follow a gradual dose-increase schedule determined by a provider
  • Side effects are generally similar and can be managed with provider support

Differences:

  • Wegovy® pen: Taken as a once-weekly injection
  • Wegovy® pill: Taken orally once per day

Your Shed provider will help determine which option may be appropriate based on your health history, preferences, and treatment goals.

Health

What’s the difference between Ozempic® and Wegovy®?

Both medications contain semaglutide, but they are FDA-approved for different uses.

  • Ozempic® is approved to treat type 2 diabetes
  • Wegovy® is specifically approved for chronic weight management

In some cases, providers may prescribe Ozempic® off-label for weight management when appropriate, but Wegovy® is the formulation designed and approved for weight loss.

Health

How does Shed’s Wegovy® program work?

Shed provides access to Wegovy® through a fully online, provider-led care model.

If prescribed, your program includes:

  • A medical review by a licensed provider
  • Ongoing provider support and follow-ups
  • Text-based Health Coaching**
  • Educational tools and resources
  • A supportive community to help you stay on track

Medication costs are separate from the monthly Shed membership.

Health

Is Wegovy® right for everyone?

Wegovy® is not appropriate for everyone. A licensed healthcare provider will review your health history and goals to determine whether Wegovy® may be a safe and suitable option for you.

Buy Naltrexone + Bupropion Online

Starting at $115/month

Naltrexone + Bupropion is a non-stimulant combination that can help support your weight management journey by working on brain pathways related to cravings, reward, and appetite regulation. This combination is non-habit-forming and may promote more mindful eating habits, especially if emotional or reward-driven eating has been a challenge. When used alongside healthy lifestyle changes, including diet and physical activity, it may contribute to sustainable weight loss over time.

Buy Naltrexone + Bupropion Online
Starting at $115/month

Naltrexone + Bupropion is a non-stimulant combination that can help support your weight management journey by working on brain pathways related to cravings, reward, and appetite regulation. This combination is non-habit-forming and may promote more mindful eating habits, especially if emotional or reward-driven eating has been a challenge. When used alongside healthy lifestyle changes, including diet and physical activity, it may contribute to sustainable weight loss over time.

Support for emotional eating habits
Craving control
Supports mood

What included in the
Shed Membership?

What's included in the
Shed Membership?

Unlimited provider visits
Shed Community access with resources, educational courses, nutrition plans, and continuous support
Support from our Member Success and medical teams every step of the way
Complimentary text-based Health Coaching** for ongoing guidance
Dedicated support on prescription orders—no more insurance hassles!
Medication not included.

What's included in the
Shed Membership?

What included in the
Shed Membership?

Unlimited provider visits
Shed Community access with resources, educational courses, nutrition plans, and continuous support
Support from our Member Success and medical teams every step of the way
Complimentary text-based Health Coaching** for ongoing guidance
Dedicated support on prescription orders—no more insurance hassles!
Medication not included.

Quiet the cravings, support new habits

A gentle aid for weight loss and well-being
Can help with food noise
Designed for emotional eaters
May reduce cravings
Personalized Health Coaching
May support improved mood
Weight management assistance
Non-stimulant formula

Shed journey

3-minute signup, 100% online
Receive a personalized plan.
Fill out a quick online form with your goals and health history. We’ll assess your eligibility and craft a personalized treatment plan just for you.
Take the leap.
Your medication will be delivered to your doorstep—no pharmacy lines, no hassle.
Experience lasting results.
Stay in touch with your Member Success Team, who are dedicated to helping you reach your desired results.

Backed by clinical insight

“Naltrexone + Bupropion is one of the few combinations studied for weight management that works by addressing emotional or reward-based eating patterns.”
Dr. Asad Niazi (MD)

Doctor of Medicine (MD),
Internal Medicine Physician

“Naltrexone + Bupropion is one of the few combinations studied for weight management that works by addressing emotional or reward-based eating patterns.”

Looking for weight-loss solutions?

While GLP-1 microdosing is ideal for maintenance, longevity, and overall wellness support, those with a significant weight-loss goal may be better suited for a standard GLP-1 dose.

Explore all our GLP-1 Solutions
100% online visit + checkout
1:1 expert care
Clinically-backed
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You’re a few clicks away from Naltrexone + Bupropion

Naltrexone + Bupropion
Starting at $115/month
1-month supply
Includes 2 Health Coaching sessions/month
Naltrexone 8 mg + Bupropion 90 mg

Questions about Buy Naltrexone + Bupropion Online? We've got answers.

What is this medication combination used for?

This combination capsule of Naltrexone + Bupropion can be used for weight management in individuals with obesity or who are generally overweight, particularly those who struggle with emotional eating or cravings.

Can this combo help with emotional eating?

Yes, that’s one of its primary benefits. It helps reduce the compulsive urge to eat in response to stress or reward-seeking.

What are the most common side effects?

Common side effects may include nausea, insomnia, dry mouth, constipation, and headache. These often improve with time.

Can I take Naltrexone + Bupropion while on antidepressants?

This depends on the antidepressant. Your provider will help you determine if you are the right candidate for this medication.

Is Naltrexone+Bupropion a stimulant?

No, it’s not classified as a stimulant, but it may still increase energy and reduce appetite.

Is this FDA-approved?

The combination of naltrexone and bupropion is FDA-approved under the brand name Contrave®. However, compounded medications themselves are not FDA-approved, even if they contain FDA-approved ingredients. Our compounded version is customized and prepared in a pharmacy to meet individual patient needs.

How does it work in the brain?

Bupropion stimulates dopamine and norepinephrine activity (curbing appetite), while Naltrexone blocks reward pathways related to food cravings.

Compounded medications are not reviewed or approved by the FDA. Prescription is only available after consultation with a licensed provider to determine if treatment is appropriate.