Weight Loss
Naltrexone + Bupropion
Starting at $115/month
Naltrexone + Bupropion is a non-stimulant combination that can help support your weight management journey by working on brain pathways related to cravings, reward, and appetite regulation. This combination is non-habit-forming and may promote more mindful eating habits, especially if emotional or reward-driven eating has been a challenge. When used alongside healthy lifestyle changes, including diet and physical activity, it may contribute to sustainable weight loss over time.
Weight Loss
Naltrexone + Bupropion
Starting at $115/month
Naltrexone + Bupropion is a non-stimulant combination that can help support your weight management journey by working on brain pathways related to cravings, reward, and appetite regulation. This combination is non-habit-forming and may promote more mindful eating habits, especially if emotional or reward-driven eating has been a challenge. When used alongside healthy lifestyle changes, including diet and physical activity, it may contribute to sustainable weight loss over time.
Ozempic®
Ozempic® helps curb appetite and support long-term weight loss.
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Mounjaro®
Mounjaro® works by targeting two key hormones to support sustainable weight loss.
Wegovy®
Wegovy® works by mimicking natural appetite-regulating hormones.
Support for emotional eating habits
Craving control
Supports mood
Quiet the cravings, support new habits
A gentle aid for weight loss and well-being
Can help with food noise
Designed for emotional eaters
May reduce cravings
Personalized Health Coaching
May support improved mood
Weight management assistance
Non-stimulant formula
How Shed works
Shed journey
3-minute signup, 100% online
Receive a personalized plan.
Fill out a quick online form with your goals and health history. We’ll assess your eligibility and craft a personalized treatment plan just for you.
Take the leap.
Your medication will be delivered to your doorstep—no pharmacy lines, no hassle.
Experience lasting results.
Stay in touch with your Member Success Team, who are dedicated to helping you reach your desired results.
Clinician-recommended
Backed by clinical insight
“Naltrexone + Bupropion is one of the few combinations studied for weight management that works by addressing emotional or reward-based eating patterns.”
Dr. Asad Niazi (MD)
Doctor of Medicine (MD),
Internal Medicine Physician
Internal Medicine Physician
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1:1 expert care
Clinically-backed
Simple, achievable results
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Subscription
Naltrexone + Bupropion
Starting at $115/month
1-month supply
Includes 2 Health Coaching sessions/month
Naltrexone 8 mg + Bupropion 90 mg
Shed FAQs
Questions about Naltrexone + Bupropion? We've got answers.
Health
What is this medication combination used for?
This combination capsule of Naltrexone + Bupropion can be used for weight management in individuals with obesity or who are generally overweight, particularly those who struggle with emotional eating or cravings.
Health
Can this combo help with emotional eating?
Yes, that’s one of its primary benefits. It helps reduce the compulsive urge to eat in response to stress or reward-seeking.
Health
What are the most common side effects?
Common side effects may include nausea, insomnia, dry mouth, constipation, and headache. These often improve with time.
Health
Can I take Naltrexone + Bupropion while on antidepressants?
This depends on the antidepressant. Your provider will help you determine if you are the right candidate for this medication.
Health
Is Naltrexone+Bupropion a stimulant?
No, it’s not classified as a stimulant, but it may still increase energy and reduce appetite.
Health
Is this FDA-approved?
The combination of naltrexone and bupropion is FDA-approved under the brand name Contrave®. However, compounded medications themselves are not FDA-approved, even if they contain FDA-approved ingredients. Our compounded version is customized and prepared in a pharmacy to meet individual patient needs.
Health
How does it work in the brain?
Bupropion stimulates dopamine and norepinephrine activity (curbing appetite), while Naltrexone blocks reward pathways related to food cravings.
Compounded medications are prepared by licensed pharmacies to meet individual patient needs. While they are not reviewed or approved by the FDA for safety or effectiveness, they are made in accordance with strict regulatory guidelines.