Weight Loss
Metformin + Naltrexone + Topiramate
Starting at $169/month
Metformin + Naltrexone + Topiramate can be helpful for those looking to support their wellness goals. This once-daily capsule is designed to fit into a balanced lifestyle, offering a needle-free and convenient approach. This option is often chosen by individuals navigating insulin resistance, blood sugar fluctuations, or stubborn weight.
Weight Loss
Metformin + Naltrexone + Topiramate
Starting at $169/month
Metformin + Naltrexone + Topiramate can be helpful for those looking to support their wellness goals. This once-daily capsule is designed to fit into a balanced lifestyle, offering a needle-free and convenient approach. This option is often chosen by individuals navigating insulin resistance, blood sugar fluctuations, or stubborn weight.
Ozempic®
Ozempic® helps curb appetite and support long-term weight loss.
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Mounjaro®
Mounjaro® works by targeting two key hormones to support sustainable weight loss.
Wegovy®
Wegovy® works by mimicking natural appetite-regulating hormones.
Mindful eating habits
Metabolic health
Balanced lifestyle
Designed to help combat cravings, insulin resistance, and PCOS
Because weight loss starts with addressing what’s underneath.
Supports mindful eating habits
Healthy appetite cues
Designed with PCOS in mind
No injections required
Insulin sensitivity
Informed by scientific research
Well-tolerated by many
How Shed works
Shed journey
3-minute signup, 100% online
Receive a personalized plan.
Fill out a quick online form with your goals and health history. We’ll assess your eligibility and craft a personalized treatment plan just for you.
Take the leap.
Your medication will be delivered to your doorstep—no pharmacy lines, no hassle.
Experience lasting results.
Stay in touch with your Member Success Team, who are dedicated to helping you reach your desired results.
Clinician-recommended
Designed for patients who’ve hit a plateau
“This triple combination is designed for patients who’ve hit a plateau. It targets insulin resistance, appetite regulation, and emotional triggers all at once.”
Dr. Asad Niazi (MD)
Doctor of Medicine (MD),
Internal Medicine Physician
Internal Medicine Physician
Be the real you
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100% online visit + checkout
1:1 expert care
Clinically-backed
Simple, achievable results
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Subscription
Metformin + Naltrexone + Topiramate
Starting at $169/month
Taken once daily
1-month supply
Includes 2 Health Coaching sessions per month
Shed FAQs
Questions about Metformin + Naltrexone + Topiramate? We've got answers.
Health
What is Metformin + Naltrexone + Topiramate?
Metformin, naltrexone, and topiramate can be used together as a triple medication strategy for managing obesity, weight loss, or metabolic syndrome. This combination capsule targets multiple pathways involved in weight regulation. Metformin improves insulin sensitivity and glucose metabolism, naltrexone reduces cravings by affecting reward pathways in the brain, and topiramate suppresses appetite and may influence satiety hormones.
Health
Is Metformin + Naltrexone + Topiramate safe?
Generally, yes, Metformin + Naltrexone + Topiramate is safe, especially when administered under medical supervision. The ingredients are naturally occurring in the body.
Health
Who is Metformin + Naltrexone + Topiramate ideal for?
Metformin + Naltrexone + Topiramate is ideal for individuals with obesity, PCOS, binge eating disorder, or insulin resistance, particularly when lifestyle changes alone are not enough.
Health
Who should not take Metformin + Naltrexone + Topiramate?
Those with significant renal or liver impairment, uncontrolled psychiatric illness, or active substance use disorder should not take Metformin + Naltrexone + Topiramate. Please speak with your provider to talk through your eligibility.
Health
Can Metformin + Naltrexone + Topiramate replace diet and exercise?
Generally, yes, Metformin + Naltrexone + Topiramate can replace diet and exercise, especially when administered under medical supervision. The ingredients are naturally occurring in the body.
Health
What are the possible side effects of Metformin + Naltrexone + Topiramate?
Possible side effects may include nausea, headache, brain fog, dizziness, and taste changes (especially from Topiramate).