Rise

Rise is positioned exactly for this: a step-up option for men who haven't had an adequate response to a single-ingredient PDE5 pill. With apomorphine, Rise supports the arousal signal from the brain, the signal that sildenafil-style pills rely on but don't create. A provider reviews your history, including what you've tried, to determine if Rise is appropriate. Individual results may vary.

Take your prescribed dose 15–60 minutes before sexual activity. The sublingual format absorbs directly into the bloodstream, bypassing digestion. Vardenafil provides rapid onset, while tadalafil's long half-life means effects can last up to 36 hours.* Never take more than one dose in 24 hours.

Although uncommon, Rise may increase the risk of an erection lasting longer than 4 hours due to its tadalafil component. If this occurs, seek immediate medical attention. Prompt treatment is important to help prevent permanent damage.

If prescribed: your medication (18 or 36 tablets per quarter, based on your plan), free discreet shipping, and unlimited provider follow-ups, including dose adjustments and safety re-screening at each renewal. No hidden fees, no insurance needed.

Certain anti-nausea medications, including ondansetron (Zofran®) and other 5-HT3 blockers, should not be taken with apomorphine because the combination can cause a dangerous drop in blood pressure and fainting. We ask about these medications to help your provider determine whether Rise is safe and appropriate for you. Be sure to tell your provider if you take or are prescribed any anti-nausea medication before or during treatment.

When prescribed appropriately after screening, Rise is generally well tolerated. Common side effects include nausea, dizziness, flushing, headache, indigestion, nasal congestion, back pain, and muscle aches. These are usually mild and temporary. Because Rise combines multiple vasoactive agents, our intake screens rigorously for cardiac history, blood pressure, and interacting medications.

Do not take Rise if you use nitrates (including prescription nitroglycerin or recreational "poppers") or riociguat — combining them can cause a dangerous drop in blood pressure.

Seek immediate medical attention if you have an erection lasting longer than 4 hours (priapism). Although rare, this is a medical emergency that can cause permanent damage if not treated promptly.

No. Your assessment is private, your medication ships in generic pharmacy packaging, your billing descriptor is discreet, and your health information is protected under HIPAA.

Rise may be eligible for HSA or FSA reimbursement. Coverage varies by plan, so check with your plan administrator to confirm eligibility.

Anytime. Discuss switching between max dose or medium dose based on your needs, step down to a single-agent option with your provider, pause, or cancel from your Shed Member Portal. No fees, no long-term contracts.