A lifestyle approach guide to sublingual GLP-1 medications: What you need to know

October 29, 2025
3 minutes
Author:
Kory Morse, MS, Head of Education at Shed

GLP-1 medications are often discussed in the context of weight management and metabolic health, but not everyone feels comfortable with injections. For some, that barrier can be enough to pause their journey. Sublingual GLP-1s*—taken as drops or lozenges that dissolve under the tongue—may feel like a more approachable option to explore with a provider.

Who sublingual GLP-1s may be for

Sublingual GLP-1s may be considered for people who:

  • Feel hesitant about injections but want to discuss alternatives with their provider.

  • Prefer convenience, since sublinguals do not involve needles.

  • They are looking for a possible starting point in their health journey while exploring long-term treatment options.

Each person’s experience is different, and whether sublinguals are a good fit should always be a decision made with your healthcare provider.

Bowl filled with rice, beans, corn, chicken, pico, and greens

Why does lifestyle play a key role?

Medication is one piece of the puzzle, but daily habits are truly the foundation. With sublinguals, the role of lifestyle support may feel even more important, since consistency in health routines can influence how well someone feels on their journey.

Core areas to focus on include:

  • Nutrition: Aim for balanced meals with protein, fiber, and nutrient-dense foods.
  • Movement: Gentle daily activity, even short walks, can provide structure and support overall well-being.
    Sleep: Rest is essential for energy, focus, and balance.
  • Stress management: Simple practices like journaling, breathwork, or light stretching can help create resilience.
  • Hydration: Is an important part of supporting your daily routine, especially when using a GLP-1 medication, as it goes beyond hydration; it supports your cells, digestion, metabolism, and helps prevent constipation. 

These habits build the foundation for a wellness plan that goes beyond medication. Partnering with a health coach can also support stronger lifestyle consistency in a way that fits your daily routine.

Common FAQs about sublingual GLP-1s

Are sublingual GLP-1s the same as injectables?
No, one is taken orally, while the other is an injectable. Individual factors always apply to treatment recommendations, so it’s important to speak with your provider to learn what may be the best fit for you.

Are they safe?
Sublingual GLP-1s should only be used under the care and guidance of a licensed healthcare provider.

Will they work for me?
Responses vary widely. Some individuals may find them helpful, while others may not. Your provider can help you track your experience and decide if adjustments are needed.

Can I switch to injectables later?
Yes, this is sometimes an option to discuss with your provider. The right path depends on your preferences, health goals, how your body responds, and individual health needs and metrics.

How long will I need to take it?
There is no single answer. The duration of any medication depends on your individual health, goals, and how your provider recommends moving forward. This is a question only you and your doctor can answer together.

The bottom line

For those who are unsure about injectables, sublingual GLP-1s may be an option to explore with a provider. Shed offers drops and lozenges, in addition to injectables, so patients, under the supervision of their provider, have a wide array of medication options to consider. While medication can be a supportive tool, your everyday habits—how you eat, move, sleep, and manage stress—are what create the strongest foundation for long-term wellness.

Disclaimers: This content is for informational and educational purposes only. It is not intended to provide medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with any questions about your health, medications, or treatment options.

*Compounded medications are not FDA-approved. They are prepared by a licensed pharmacy based on a provider’s prescription.

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