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This month, the World Health Organization (WHO) released its first-ever global guidelines on the use of GLP-1 treatments for the long-term treatment of obesity in adults.
These guidelines are important. They help set clear expectations around how GLP-1 therapies are meant to be used and what actually supports long-term success.
Key takeaway from the WHO guidelines
- GLP-1 therapies may be used long-term by adults with obesity when prescribed and monitored by a medical provider.
- Medication works best when combined with intentional lifestyle support, including balanced nutrition, regular physical activity, and ongoing behavioral guidance to help sustain both weight loss and metabolic health.
- Treatment should be part of a comprehensive, person-centered care plan, not a standalone “quick fix.”
The WHO emphasizes that GLP-1 therapies are powerful tools, and lasting success depends on lifestyle changes, access to care, and a long-term commitment.
Why these guidelines matter
The WHO recognizes obesity as a chronic disease, not simply a lifestyle choice. Their guidance reflects what the science continues to show: GLP-1 therapies work best when paired with lifestyle habit change and ongoing behavioral support.
Rather than promoting quick fixes or fad diets, the WHO emphasizes a holistic, sustainable approach to weight and metabolic health, one that supports the whole person over time.
How Shed follows and embodies WHO principles
At Shed, our model is built around these same principles.
Medical supervision: Members work with licensed practitioners who prescribe treatment and provide guidance throughout their journey.
Metabolic foundation nutrition plan: A structured nutrition framework focused on protein, fiber, nutrient density, and gut health to support GLP-1 use and metabolic health.
Shed GLP-1 weight-loss and reset program: A guided lifestyle program with step-by-step lessons designed to build sustainable habits across nutrition, movement, sleep, and stress management.
Shed Community: An educational and supportive member platform offering courses, guides, recipes, shared experiences, and ongoing connection.
Shed supplements: Thoughtfully formulated support for metabolism, digestion, muscle preservation, and overall vitality.
Weight maintenance and graduation program: Members are supported through a transition into maintenance, helping them carry habits forward into long-term, sustainable wellness.
The big picture: Why a combined approach matters
GLP-1 medications are a breakthrough in medical intervention, but the WHO is clear that medication alone won’t solve the obesity epidemic. What really transforms health is a sustainable healthy lifestyle. That’s why Shed was built the way it is to offer treatment and transformation, rooted in science, compassion, and personal lifestyle support.
Frequently asked questions: WHO GLP-1 guidelines for long-term weight loss
Does the WHO recommend GLP-1 medications for long-term use?
Yes. The WHO recognizes obesity as a chronic disease and supports long-term use of GLP-1 medications when clinically appropriate. Ongoing medical supervision, lifestyle changes, and behavioral support are considered essential for maintaining weight loss and metabolic health over time.
Why does the WHO stress lifestyle changes alongside GLP-1 treatment?
GLP-1 medications are powerful tools, but lasting weight loss and metabolic changes depend on behavioral change; medication alone is insufficient. Balanced nutrition, regular physical activity, stress management, and quality sleep all play a critical role in long-term success.
How will the WHO guidelines change the way obesity is treated?
These guidelines reinforce that obesity is a medical condition requiring long-term care, rather than short-term interventions or willpower-based approaches. This will shift treatment toward sustainable, medically guided treatment that supports the whole person rather than just the number on the scale.
Why is medical supervision important when using GLP-1 medications?
Medical oversight ensures GLP-1 therapies are used safely and appropriately over time. Shed providers take into account your medical history and goals to help manage dosing, side effects, and progress over time.
Who is an appropriate candidate for GLP-1 therapy under the new WHO guidelines?
GLP-1s may be considered for adults with obesity when determined clinically appropriate by a licensed provider and when access to medical monitoring and lifestyle support is available.
How does Shed align with WHO GLP-1 guidelines?
Shed’s care model aligns with WHO’s GLP-1 recommendations. We combine medical supervision, structured nutrition guidance, behavioral education, and long-term support to support the whole individual. GLP-1 treatment at Shed is integrated into a broader lifestyle framework designed to help members build habits they can maintain beyond active weight loss.
This information is for educational purposes only and is not a substitute for medical advice. Please consult your healthcare provider before starting or changing any medication.
