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Starting a GLP-1 weight-loss injection is a significant milestone in your health journey. Whether you're considering a brand-name or compounded version, it's essential to make an informed, safe, and personalized decision.
GLP-1 medications, like those offered through Shed, are never a one-size-fits-all solution. To support your decision, use this guide to ask the right questions before beginning your medication-supported program.
What medication am I being prescribed?
- Is this the same active ingredient found in Ozempic®, Wegovy®, Mounjaro®, or Zepbound®?
- Am I receiving a brand-name or compounded version? (It's important to understand your prescription details so you know exactly what's being dispensed.)
Tip: Most programs, including Shed, start with a detailed consultation. During intake, you'll complete a health questionnaire.Your provider reviews your medical history, BMI, and health status to ensure you're eligible—and that you're matched with the right treatment.
What can I expect in terms of benefits, and how soon will I see results?
- What is the anticipated timeline for weight loss?
- How can I measure success beyond the scale?
Many individuals on GLP-1 therapy notice changes in blood sugar, blood pressure, and overall energy alongside weight reduction, especially when paired with nutrition coaching and tracked physical activity.
Recent findings highlight that GLP-1 receptor agonists are capable of producing significant weight loss and even reducing the risk of serious cardiovascular events for people with obesity. For example, a global study of 3.7 million individuals found that GLP-1 therapy was linked to lower all-cause mortality and fewer complications such as heart failure or stroke (source). Furthermore, a comprehensive review of randomized controlled trials showed that GLP-1 medications led to an average weight loss of 4.57 kg and a significant reduction in BMI (source).
Did you know? Shed offers a weight-loss guarantee for qualifying members. If you follow all program requirements and don’t achieve at least a 10% reduction in body weight within nine months, you may be eligible for a refund or program credit. Full details are in our terms and conditions.
What are the potential side effects of GLP-1 medications?
While GLP-1 medications are well-tolerated, you might experience temporary effects as your body adjusts—such as nausea, indigestion, constipation, diarrhea, headache, fatigue, or injection site reactions.
Effects are often more noticeable when starting or adjusting your dose. Eating slowly, hydrating, and choosing smaller, balanced meals can help. Most members report that these side effects ease naturally in a few weeks.
As outlined in a recent systematic review, the most common side effects for adults using GLP-1 receptor agonists included mild to moderate gastrointestinal symptoms, such as nausea and diarrhea (source). In addition, real-world analysis of FDA adverse event data has shown that gastrointestinal issues are a recognized risk, particularly with semaglutide and exenatide, and very rarely, delayed gastric emptying or pancreatitis can occur (source).
Important: If symptoms persist or become intense, contact your prescribing provider right away. If anything feels urgent, seek immediate care. Shed's Member Success Team is always here to support and guide you.
What should I do if I miss a dose?
Consistency is key. If you skip a dose, reach out to the Shed Member Success Team or your provider for step-by-step advice—it can vary by medication and timing.
Set calendar reminders or alarms to help keep your schedule on track.
Are there medical reasons I shouldn't take this medication?
Yes. Let your provider know if you have a history of thyroid cancer, pancreatitis, gallbladder disease, or other major health concerns.
Certain medications may interact with GLP-1s. Always review your full medication list with your prescribing clinician before starting.
What lifestyle changes should I make alongside this medication?
Focus on nutrition, regular exercise, and hydration for optimal results.
Shed's Coaching Program includes tailored meal plans, exercise guidance, and ongoing support—all designed to help you achieve long-term success with your medication.
Combining lifestyle changes with GLP-1 therapy produces the strongest and most sustainable results, as highlighted in several large-scale independent reviews, including a meta-analysis confirming a positive impact on weight, BMI, and waist circumference (source).
How long will I be on this treatment?
Treatment length varies. Some members use it as a short-term jumpstart, while others make it part of a longer wellness plan.
Only discontinue or change your regimen per your provider's instructions—direct guidance is essential for safety and maintaining results.
A systematic literature review further supports that GLP-1 programs, such as those including semaglutide, offer notable long-term benefits in weight management as well as improvements in blood sugar control (source).
What is the cost, and is it covered by insurance?
Monthly subscription pricing depends on medication type and dosage.
Some programs (including those with compounded medications) offer cash-pay models for affordability.
Additional questions for compounded medication
If your provider prescribes a compounded GLP-1 version, ask:
Is this medication made from a semaglutide or tirzepatide base?
FDA guidance advises use only of approved forms. Avoid sodium or acetate versions that aren't sanctioned for weight loss.
Is the pharmacy fully accredited and in good standing?
Verify if the pharmacy is a 503A or 503B facility, and check if it's accredited (e.g., PCAB).
Reputable programs like Shed's only partner with pharmacies following rigorous safety and licensing standards.
Is there independent testing for potency and sterility?
Confirm third-party testing is performed. Reliable compounders (such as those working with Shed) ensure every batch meets strict quality standards.
What's the dosing protocol?
Dosing is never self-directed—your licensed healthcare provider determines your schedule and makes adjustments based on ongoing labs and clinical review.
What happens if compounded versions become unavailable due to regulation?
Availability can depend on whether your pharmacy is a 503A or 503B, and current state or federal rules.
Shed maintains access to both pharmacy types, helping you navigate changes and maintain continuity of care under licensed supervision.
Final tips for a safe start
Track your symptoms—keeping a simple log helps you and your provider work together to fine-tune your response and dose.
Follow all titration instructions exactly. Never increase dose faster than prescribed; this helps prevent unnecessary side effects and supports weight-loss safety.
GLP-1 medications represent a true paradigm shift in obesity treatment, actively suppressing appetite and supporting healthy, sustained weight loss—positioned as one of the most significant advancements in years (source).
How do you keep yourself safe and confident during your journey?
Protect your health and investment by asking questions, verifying every detail, and building a partnership with your care team. At Shed, we encourage you to be proactive. The path to long-term, sustainable weight loss starts with getting all the facts—and knowing your provider is here every step.
Frequently asked questions (FAQ) about GLP-1 weight-loss programs
Can I get a Wegovy® or Ozempic® prescription online—with regular doctor check-ins?
Yes. GLP-1 medications—including compounded alternatives—are available through secure virtual consults with licensed healthcare providers. At Shed, telehealth members receive ongoing guidance, check-ins, and access to our Member Success Team, so your progress is continually monitored.
What's included in a Shed GLP-1 weight-loss program besides the medication?
Shed's programs are holistic. Alongside GLP-1 injections, you get nutrition coaching, lab tracking, compliance support, and goal-based check-ins. Our care model emphasizes partnership and accountability for the best clinical and lifestyle outcomes.
How do I compare prices for GLP-1 medications in 2025?
Medication costs vary based on brand, compounded options, and insurance coverage. Shed offers transparent monthly pricing. so you can compare options with confidence.
What is the easiest way to travel with GLP-1 injections and meet TSA guidelines?
When flying, keep your GLP-1 medication in a carry-on bag, and use an FDA-approved sharps container for used syringes. For medications requiring refrigeration, use an insulated cooler or ice packs, and bring your prescription with a label for TSA verification. Check your airline's and TSA's latest policies before departure.
Are there programs that start with low-dose or micro-dosing protocols?
Yes. Many modern telehealth platforms, including Shed, offer microdosing options under provider guidance. How does Shed ensure my medication is safe and sourced properly?
Shed only partners with licensed, accredited, and experienced pharmacies—503A and 503B—to maintain the highest safety and regulatory standards. All compounded options undergo third-party potency and sterility testing before delivery.
Have more questions or need a personalized answer? Contact the Shed Member Success Team or join our waitlist. Our experts are ready to guide you on every step of your GLP-1 journey.
