Metabolism and weight loss: How to boost your body's fat-burning potential

September 16, 2025
5 minutes
Author:
Angie Carter, Health Writer at Shed

You've been diligently following your diet plan and hitting the gym regularly, yet the stubborn scale refuses to budge. Frustrating, isn't it? Despite your efforts, achieving weight loss goals can sometimes feel like an uphill battle. However, understanding the intricate relationship between metabolism and weight loss—and knowing which medical and lifestyle interventions can help—can make a real difference.

At Shed, we understand that lasting weight loss requires more than just willpower—it requires a comprehensive approach that addresses your unique metabolic needs. That's why we combine evidence-based lifestyle strategies with advanced medical interventions like GLP-1 medications and targeted supplements to help optimize your body's natural fat-burning potential.

Here's your guide to effective strategies and modern medication options that can help rev up your body's fat-burning potential, optimize your results, and achieve your desired weight loss and wellness goals.

1. Nourish your body with metabolism-boosting foods

When it comes to optimizing your metabolism, the foods you eat play a critical role. Focus on incorporating metabolism-boosting foods into your diet, such as lean proteins like chicken, fish, tofu, and beans. These foods require more energy for digestion, which means your body burns more calories processing them[1]. Additionally, whole grains like quinoa, brown rice, and oats provide sustained energy and keep your metabolism humming along. Don’t forget to load up on fruits and vegetables, which are rich in vitamins, minerals, and antioxidants. Chili peppers, in particular, contain capsaicin, which may increase metabolic rate and promote fat loss[2].

For maximum impact, complement your meals with high-fiber foods to promote satiety and support your body's natural GLP-1 production. For more about the hormone connection, check out our article on balancing hormones for optimal weight loss and wellness.

2. Amp up your activity levels with high-intensity interval training (HIIT)

High-Intensity Interval Training (HIIT) is a powerful tool for supercharging your metabolism and torching calories. Unlike steady-state cardio, HIIT workouts involve short bursts of intense activity followed by brief recovery periods[3]. This elevates your heart rate and keeps your metabolism revved up long after your workout is over, leading to increased calorie burn throughout the day. Incorporate HIIT exercises like sprints, jump squats, and mountain climbers into your routine to maximize fat loss and improve cardiovascular health.

3. Prioritize quality sleep for optimal metabolic function

Quality sleep is essential for metabolic health and weight management. When you’re sleep-deprived, hormone levels like cortisol, insulin, and leptin become imbalanced, which can lead to increased appetite, cravings for sugary and high-fat foods, and a slower metabolism. Aim for 7-9 hours of uninterrupted sleep each night to support optimal hormone regulation, metabolic function, and overall well-being. Establish a relaxing bedtime routine, limit screen time before bed, and create a comfortable sleep environment to ensure restorative sleep each night.

4. Stay hydrated to boost your metabolism

Drinking water not only keeps you hydrated but also temporarily boosts your metabolic rate. Research suggests that drinking water can increase the number of calories your body burns at rest for up to 90 minutes after consumption. Staying hydrated is key to boosting metabolism and efficient calorie burning[4]. Aim to drink at least 8-10 cups of water per day and consider incorporating hydrating foods like cucumber, watermelon, and oranges into your diet.

5. Incorporate strength training to build metabolism-boosting muscle

Strength training is a crucial component of any metabolism-boosting fitness routine. Unlike cardio exercises, which primarily burn calories during the workout, strength training builds lean muscle mass, which boosts your metabolism around the clock. Muscle tissue is more metabolically active than fat tissue, meaning it burns more calories at rest. Incorporate strength training exercises like weight lifting, bodyweight exercises, and resistance band workouts into your routine at least two to three times per week to build muscle, increase metabolism, and improve body composition.

6. Understand the role of hormones in metabolism and weight loss

Hormones play a significant role in regulating metabolism and body weight. Imbalances in hormones like insulin, cortisol, thyroid hormones, and leptin can impact metabolic function and contribute to weight gain. Consult with a healthcare professional to assess hormone levels and address any underlying imbalances through targeted interventions such as medication, lifestyle modifications, or dietary changes. By addressing hormonal imbalances, you can support optimal metabolic function and improve weight loss outcomes. Learn more about hormone balance and weight loss here.

7. Optimize your diet for metabolic efficiency

In addition to individual foods, the overall composition of your diet can influence metabolic function and weight loss. Aim for a balanced diet rich in whole, nutrient-dense foods, including lean proteins, complex carbohydrates, healthy fats, and plenty of fruits and vegetables. Fiber-rich foods like vegetables, fruits, legumes, and whole grains promote satiety, stabilize blood sugar levels, and support digestive health, all of which are essential for a healthy metabolism. Legumes and pulses such as lentils, beans, and chickpeas are especially beneficial, as they are high in protein and fiber, requiring more energy to digest and supporting metabolism[5]. Minimize processed foods, sugary snacks, and refined carbohydrates, which can lead to blood sugar spikes and crashes. Instead, focus on nourishing your body with nutrient-rich foods.

8. Consider weight-loss medications

If lifestyle modifications alone are not sufficient, medical interventions such as prescription weight-loss medications can be considered. Drugs like Compounded Semaglutide and Mounjaro® have shown promising results in aiding weight loss by suppressing appetite and improving metabolic parameters. Clinical studies have shown that Semaglutide and Mounjaro® can help patients lose 10% to 15% of their initial body weight within a few weeks. The availability of GLP-1 agonists like Wegovy® has transformed obesity treatment, offering significant weight loss by mimicking hormones that control appetite[6]. Additionally, GLP-1 receptor agonists have demonstrated efficacy in reducing A1C and promoting weight loss[7].

What are GLP-1 medications?

Compounded Semaglutide and Mounjaro® are promising medications for weight loss. Compounded Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that mimics the effects of the hormone GLP-1, which regulates appetite and blood sugar levels. It has been approved for the treatment of type 2 diabetes and has shown significant weight loss. Mounjaro® is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist that also demonstrates potent weight loss effects by targeting multiple pathways involved in appetite regulation.

There are now also oral alternatives in development, such as Eli Lilly's GLP-1 pill, which achieved an average weight loss of 12.4% in late-stage trials[8].

Curb appetite and avoid overeating

Compounded Semaglutide and Mounjaro® are GLP-1 receptor agonists, which means they mimic the effects of the naturally occurring hormone GLP-1 in the body. GLP-1 plays a crucial role in appetite regulation by signaling to the brain to reduce hunger and increase feelings of fullness. By activating GLP-1 receptors, Compounded Semaglutide and Mounjaro® help control appetite, helping individuals consume fewer calories and maintain a calorie deficit necessary for weight loss.

Delay gastric emptying and avoid snacking

In addition to controlling appetite, Compounded Semaglutide and Mounjaro® also slow down the emptying of the stomach, a process known as gastric emptying. Slower gastric emptying prolongs the time it takes for food to leave the stomach and enter the small intestine, resulting in increased feelings of fullness and reduced hunger between meals. By delaying gastric emptying, these medications help you avoid snacking between meals.

Promote healthier food choices

Individuals taking Compounded Semaglutide and Mounjaro® often report a shift toward healthier food choices. This change in dietary preferences is attributed to the appetite-suppressing effects of these medications, which reduce cravings for high-calorie, processed foods and increase satiety from nutrient-dense options. By promoting a preference for healthier food choices, Compounded Semaglutide and Mounjaro® support sustainable weight loss and long-term health improvements.

Get your Semaglutide and prescriptions

Shed offers convenient telehealth access to weight-loss medications like Compounded Semaglutide. Through our online platform, you can schedule a virtual consultation with a healthcare provider who will assess your medical history, weight-loss goals, and suitability. You'll have the opportunity to discuss any concerns or questions you may have, and a provider will determine the appropriate dosage and medications for your needs. Once prescribed, we'll deliver your medications to your chosen address.

9. Boost metabolism with weight-loss supplements

While diet and exercise are essential components of any weight loss plan, certain supplements can also support metabolic function and enhance fat loss. Look for supplements containing ingredients like green tea extract, caffeine, and conjugated linoleic acid (CLA), which have been shown to increase metabolism and promote fat oxidation. Even ginger has metabolism-boosting properties and may add to calorie burn when incorporated into your routine[9]. When used appropriately, weight-loss supplements can contribute to your overall success in achieving your weight loss goals. Shed offers numerous weight-loss supplements that can boost metabolism and complement your weight-loss medications, helping you achieve your ideal weight.

10. Prioritize protein-rich foods

Protein is essential for muscle repair and growth and plays a crucial role in supporting a healthy metabolism. Foods rich in protein require more energy to digest than carbohydrates and fats, resulting in a temporary increase in calorie expenditure known as the thermic effect of food (TEF)[1]. Aim to include protein-rich foods like lean meats, fish, eggs, dairy products, legumes, and tofu in your meals and snacks to maximize TEF and support weight loss.

11. Embrace mindful eating practices

Mindful eating involves paying attention to your food choices, hunger cues, and eating habits without distraction. By practicing mindfulness during meals, you can develop a deeper awareness of your body’s hunger and fullness signals, leading to more mindful food choices and improved portion control. Eating slowly, savoring each bite, and tuning into your body’s hunger and satiety cues can help prevent overeating, promote better digestion, and support a healthy metabolism.

By implementing these strategies, you can optimize your metabolism and enhance your body’s fat-burning potential, making it easier to achieve your weight loss goals. Take charge of your health and watch as your body transforms into a leaner, healthier version of itself.

Frequently asked questions: Affordable weight-loss medications and combinations

What are the best compounded alternatives to brand-name weight loss medications?

Compounded GLP-1 medications like semaglutide and tirzepatide—custom mixed by licensed compounding pharmacies—offer more affordable, accessible alternatives to brand-name drugs. Shed partners only with reputable sources to deliver quality compounded medications directly to your door. All compounded medications are only prescribed when deemed medically necessary by a healthcare professional. Connect with a provider today to determine your eligibility. 

What supplements are recommended to use alongside weight-loss medications?

If you’re on weight-loss medication, supplements like fiber, green tea extract, magnesium, and CLA can help boost results when integrated thoughtfully. The Shed team can help you select supplements that best complement your prescribed plan.

What are budget-friendly options for medication-based weight management?

Compounded versions of semaglutide and tirzepatide, are typically more wallet-friendly than brand-name options. Explore GLP-1 injections and compounded solutions here and consult with our team and a provider for the current best options and pricing.

Are there clinics or platforms offering comprehensive support with medication, supplements, and nutrition?

Shed combines access to medication with ongoing support, evidence-based supplement recommendations, and nutrition plans. Explore all weight loss products and coaching options in one place.

What are the risks of compounded medications, and how does Shed keep me safe?

While compounded GLP-1s are not FDA-approved in their mixed form, Shed exclusively uses licensed, reputable US pharmacies, ensuring rigorous quality and oversight. We partner with providers who monitor your progress and safety throughout your journey.

Who provides cost-effective online GLP-1 medication delivery?

Shed’s secure telehealth platform makes branded and compounded GLP-1 medications accessible nationwide, providing timely, budget-friendly solutions and ongoing clinician support.

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