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*In clinical trials studying Wegovy® (2.4 mg), the average weight loss was 15% and 20%, respectively, when paired with diet and exercise (compared to 2.4% and 3.1% with diet and exercise alone). Results may vary. Compounded medications are not FDA-approved and are made by a licensed pharmacy based on a provider’s prescription.

CJC-1295 + Ipamorelin Protocol

Supports growth hormone signaling through two complementary pathways — under physician supervision with lab monitoring
Starting at $XXX/month
Supports the body's own GH and IGF-1 production
Minimal cortisol or prolactin impact
Timed nightly to align with the body's natural GH rhythm
CJC-1295 and Ipamorelin work through distinct receptor pathways to support your body's own growth hormone release. CJC-1295 primes the pituitary; ipamorelin amplifies GH pulses. Together, they represent the most widely discussed GH peptide combination in personalized medicine.
*In clinical trials studying Wegovy® (2.4 mg), the average weight loss was 15% and 20%, respectively, when paired with diet and exercise (compared to 2.4% and 3.1% with diet and exercise alone). Results may vary. Compounded medications are not FDA-approved and are made by a licensed pharmacy based on a provider’s prescription.
FAQ

Is CJC-1295 + Ipamorelin FDA approved?

No. Neither compound is FDA-approved for the indications discussed, and both are subject to current compounding restrictions. Shed is prepared to offer them when regulations allow.
FAQ

Do I need labs first?

FAQ

How long is a protocol?

FAQ

How is it delivered?

  Physician Supervised  •  Lab-Monitored  •  FDA-Registered Pharmacy  •  Evidence-Reviewed  •
 Physician Supervised  •  Lab-Monitored  •  FDA-Registered Pharmacy  •  Evidence-Reviewed  •
  Physician Supervised  •  Lab-Monitored  •  FDA-Registered Pharmacy  •  Evidence-Reviewed  •
What is CJC-1295 + Ipamorelin
CJC-1295 is a synthetic analog of Growth Hormone Releasing Hormone (GHRH) — the same signal your hypothalamus uses to tell your pituitary to produce growth hormone. Ipamorelin is a selective ghrelin receptor agonist that amplifies GH pulses through a completely separate receptor pathway.

Used together, researchers describe this as dual-pathway GH stimulation — CJC-1295 drives GH synthesis while ipamorelin increases the size of each GH pulse. What distinguishes ipamorelin from older GHRPs is its selectivity: it stimulates GH release without meaningfully raising cortisol or prolactin.

Published human data confirms CJC-1295 produces sustained GH and IGF-1 elevation while preserving the natural pulsatile pattern of GH secretion — a key physiological advantage over exogenous GH.

Benefit deep dive

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Daily support to help maintain cellular energy.

Growth Hormone Axis Support

Researchers have documented CJC-1295 producing 2–10 fold increases in GH and sustained IGF-1 elevation in human trials — one of the more pharmacologically credible GH stimulation results in the literature.

Selective, Clean GH Release

Preserved Pulsatility

Recovery & Sleep Quality

Individual experiences vary. These statements describe general physiological roles of NAD+.

How CJC-1295 + Ipamorelin Works

Designed to support circulation and the body’s natural recovery pathways
1.
GHRH Receptor Activation (CJC-1295)

CJC-1295 binds to GHRH receptors on pituitary somatotrophs, stimulating GH synthesis and release — using the same receptor pathway your hypothalamus uses naturally.

2.
Ghrelin Receptor Amplification (Ipamorelin)

Ipamorelin binds the ghrelin receptor (GHS-R1a) through a completely separate intracellular pathway, amplifying the magnitude of each GH pulse synergistically.

3.
Synergistic Output

The two receptor systems use distinct signaling cascades — cAMP for CJC-1295; phospholipase C for ipamorelin — producing additive amplification beyond what either compound achieves alone.

Your CJC-1295 + Ipamorelin plan, made simple

3-minute medical intake. Provider-led. 100% online.
Step 1
Complete your online consultation

You fill out a brief medical intake about your goals, symptoms, and health history. This helps your provider determine if CJC-1295 + Ipamorelin is appropriate for you.

Step 2
Provider review & personalized plan

A licensed clinician reviews your case and creates a tailored CJC-1295 + Ipamorelin plan based on your needs.

Step 3
Medication compounded & shipped to you

If approved, your CJC-1295 + Ipamorelin is prepared by a U.S.-based compounding pharmacy and delivered directly to your door.

Step 4
Ongoing support inside your Shed portal

Ask questions, request adjustments, and get support anytime from your care team.

Shed FAQs

Questions? Answers.

Joining

Is CJC-1295 + Ipamorelin FDA approved?

No. Neither compound is FDA-approved for the indications discussed, and both are subject to current compounding restrictions. Shed is prepared to offer them when regulations allow.
Joining

Do I need labs first?

Joining

How long is a protocol?

Joining

How is it delivered?