*In clinical trials studying Wegovy® (2.4 mg), the average weight loss was 15% and 20%, respectively, when paired with diet and exercise (compared to 2.4% and 3.1% with diet and exercise alone). Results may vary. Compounded medications are not FDA-approved and are made by a licensed pharmacy based on a provider’s prescription.

GHK-Cu

Supports skin regeneration, collagen biology, and wound repair under physician supervision.

Starting at $XXX/month

GHK-Cu is a copper-binding tripeptide that occurs naturally in the human body — and its plasma levels decline measurably with age. Studied in published human clinical trials, it is the best-evidenced peptide on Shed's list for skin repair and wound healing biology.

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FAQ

Is GHK-Cu FDA approved?

Not as a drug. Topical GHK-Cu has an established cosmetic safety record; injectable use is investigational and physician-supervised at Shed.

FAQ

Do I need a prescription?

FAQ

How long does a protocol last?

FAQ

How is it delivered?

Provider Supervised • FDA-Registered Pharmacy • Personalized Protocols • Evidence-Reviewed •

What is GHK-Cu?

GHK-Cu (Glycyl-L-Histidyl-L-Lysine : Copper II) is a naturally occurring tripeptide first identified in human plasma in 1973 by researcher Loren Pickart. It functions as a copper chaperone — delivering copper ions to tissues where they're needed for collagen synthesis, enzymatic activity, and cellular repair.

What makes GHK-Cu scientifically compelling is its age-related decline: plasma concentrations fall from approximately 200 ng/mL at age 20 to around 80 ng/mL by age 60 — prompting researchers to study whether GHK-Cu can help support the biological processes it's associated with as we age.

Unlike most peptides on Shed's list, GHK-Cu has published human RCT data for topical applications — specifically in skin firmness, photoaging, and wound healing contexts.

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Benefit deep dive

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Daily support to help maintain cellular energy.

Skin Firmness & Elasticity

A 12-week double-blind human study showed significant improvement in skin laxity and fine lines in GHK-Cu treated participants versus placebo, one of the strongest human datasets for any cosmetic peptide.

Collagen Architecture Support

Wound Healing Biology

Broad Cellular Renewal

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See if you qualify →

How GHK-Cu Works

Designed to support circulation and the body’s natural recovery pathways

Copper Delivery

GHK-Cu acts as a carrier, delivering copper ions to tissues where they activate enzymes essential for collagen cross-linking, elastin formation, and wound repair.

Fibroblast Stimulation

Research shows GHK-Cu directly stimulates fibroblast activity, the cells responsible for producing collagen and the structural proteins that give skin its firmness and resilience.

Anti-Fibrotic Signaling

GHK-Cu has been studied for its ability to inhibit TGF-beta-driven fibrosis, the process underlying excessive scarring, suggesting a role in balanced tissue remodeling rather than scar formation.

Your GHK-Cu plan, made simple

3-minute medical intake. Provider-led. 100% online.

Step 1

Complete your online consultation

You fill out a brief medical intake about your goals, symptoms, and health history. This helps your provider determine if GHK-Cu is appropriate for you.

Step 2

Provider review & personalized plan

A licensed clinician reviews your case and creates a tailored GHK-Cu plan based on your needs.

Step 3

Medication compounded & shipped to you

If approved, your GHK-Cu medication is prepared by a U.S.-based compounding pharmacy and delivered directly to your door.

Step 4

Ongoing support inside your Shed portal

Ask questions, request adjustments, and get support anytime from your care team.

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