Metformin, naltrexone, and topiramate can be used together as a triple medication strategy for managing obesity, weight loss, or metabolic syndrome. This combination capsule targets multiple pathways involved in weight regulation. Metformin improves insulin sensitivity and glucose metabolism, naltrexone reduces cravings by affecting reward pathways in the brain, and topiramate suppresses appetite and may influence satiety hormones.

Generally, yes, Metformin + Naltrexone + Topiramate is safe, especially when administered under medical supervision. The ingredients are naturally occurring in the body.

Metformin + Naltrexone + Topiramate is ideal for individuals with obesity, PCOS, binge eating disorder, or insulin resistance, particularly when lifestyle changes alone are not enough.

Those with significant renal or liver impairment, uncontrolled psychiatric illness, or active substance use disorder should not take Metformin + Naltrexone + Topiramate. Please speak with your provider to talk through your eligibility.

Generally, yes, Metformin + Naltrexone + Topiramate can replace diet and exercise, especially when administered under medical supervision. The ingredients are naturally occurring in the body.

Possible side effects may include nausea, headache, brain fog, dizziness, and taste changes (especially from Topiramate).