3-in-1 ED
One dose, 3x the power

Rise

Rapid-dissolve 3-in-1 ED medication that primes the brain for arousal and powers blood flow.

  • Take 15–60 minutes before sex, built for spontaneity
  • Sublingual tablet that dissolves under the tongue, no water needed
  • 100% online, prescribed by U.S.-licensed providers
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How Rise works
A fast-acting, on-demand ED treatment that combines three actives: tadalafil and vardenafil for blood flow, and apomorphine for the brain's arousal signal. Rise addresses both the physical and mental components of erections, and is positioned as a step-up option for men who haven't had an adequate response to a single-ingredient pill.
How do I take Rise?
Place one tablet under your tongue and let it dissolve, 15–60 minutes before sexual activity. Do not take more than one dose in 24 hours, and do not combine with any other ED medication.
How is Rise different from other ED meds?
Single-ingredient pills work on one pathway: blood flow. Rise pairs two complementary PDE5 inhibitors (vardenafil for rapid onset, tadalafil for extended duration) with apomorphine, a centrally acting dopamine agonist that facilitates the brain's erectile response. Body and brain, one tablet.
150k+ Shed members U.S.-licensed providers No surprises, upfront pricing Personalized support 100% entirely online FSA and HSA eligible Free and discreet shipping Customized to your needs Licensed U.S. pharmacy 150k+ Shed members U.S.-licensed providers No surprises, upfront pricing Personalized support 100% entirely online FSA and HSA eligible Free and discreet shipping Customized to your needs Licensed U.S. pharmacy

Take back your best nights

Provider-prescribed treatment powered by three clinically studied actives.

Blood vessels carrying illuminated particles, visualizing the dual-pathway mechanism

Dual-pathway formula

Designed to support arousal and blood flow, not just one or the other

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Fast-acting onset

Take 15–60 minutes before sex. Sublingual, built for spontaneity

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Extended window

Tadalafil's effects can last up to 36 hours*

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Discreet & 100% online

Clinician-reviewed intake, plain packaging, unlimited follow-up

‹ swipe › *Reflects tadalafil's established duration profile. Compounded medications are not FDA-approved. Individual results vary.
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Why Rise works

Great sex starts in the brain

01

Without the brain's signal, blood flow alone won't do it

An erection needs two things: an arousal signal from the brain and healthy blood flow to respond to it. That's why traditional ED pills work for some men sometimes, but not always. The plumbing is treated. The signal isn't.

02

Rise targets both: signal and response

Apomorphine acts on dopamine receptors in the hypothalamus to facilitate the brain's erectile response, while tadalafil and vardenafil handle blood flow. You're addressing the full mechanism, not half of it.

See if Rise is right for you
The formula

Three medications, one tablet

Each active earns its place: one for the brain, two for the body.

Two Rise 3-in-1 ED tablet bottles
Apomorphine 3mg · Dopamine agonist Primes the brain's arousal signal, acting on dopamine receptors in the hypothalamus.
Tadalafil 20mg · PDE5 inhibitor Sustains blood flow with a long half-life, keeping the window open up to 36 hours.*
Vardenafil 15mg · PDE5 inhibitor Rapid-onset blood flow support that covers the moment while tadalafil covers the night.
Simple from the start

How it works.

1

Fill out a 5-minute form online

Answer a few questions about your health history and goals, all online. No appointment required.

2

A licensed provider reviews your answers

They look at your health history and goals, and prescribe only if it's right for you.

3

Your treatment ships straight to you

Free, discreet shipping. The box shows a pharmacy name, never Shed or any product details.

Which treatment is right for you?

Rise 3-in-1 ED tablet bottle
Rise
3-in-1 ED tablet
Steady tadalafil daily tablet bottle
Steady
Daily ED tablet
Extend 3-in-1 PE tablet bottle
Extend
3-in-1 PE tablet
Made for Men who want on-demand performance, especially when single-ingredient pills underdelivered Men who prefer one daily tablet and full spontaneity, with no timing required Men who want more control over timing and lasting longer
Benefits Designed to support arousal and blood flow: brain and body in one tablet Designed for consistent, background erectile support, every day Designed to delay ejaculation and support control and confidence
Formula Apomorphine 3mg, Tadalafil 20mg, Vardenafil 15mg Tadalafil 5mg Paroxetine 20mg, Tadalafil 5mg, L-Theanine 50mg
Usage One sublingual tablet 15–60 minutes before sex, max one per 24 hours One tablet daily, around the same time each day One tablet 1–3 hours before sex, max one per 24 hours
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All treatments are prescription-only, prescribed by a licensed provider if appropriate. Compounded medications are not FDA-approved.

Questions? Answers.

Frequently asked questions

If Viagra® or Cialis® didn't work for me, will Rise?
Rise is positioned exactly for this: a step-up option for men who haven't had an adequate response to a single-ingredient PDE5 pill. With apomorphine, Rise supports the arousal signal from the brain, the signal that sildenafil-style pills rely on but don't create. A provider reviews your history, including what you've tried, to determine if Rise is appropriate. Individual results vary.
How fast does Rise work, and how long does it last?
Take one tablet 15–60 minutes before sexual activity. The sublingual format absorbs directly into the bloodstream, bypassing digestion. Vardenafil provides rapid onset, while tadalafil's long half-life means effects can last up to 36 hours.* Never take more than one dose in 24 hours.
What's included in the price?
If prescribed: your medication (12 or 18 tablets per quarter, based on your plan), free discreet shipping, and unlimited provider follow-ups, including dose adjustments and safety re-screening at each renewal. No hidden fees, no insurance needed.
Why do you ask about anti-nausea medication?
Certain anti-nausea medications (5HT3 blockers such as Zofran/ondansetron) can cause dangerously low blood pressure and fainting when combined with apomorphine. It's an absolute hard stop, which is why our intake asks explicitly, and why you should tell your provider if you're ever newly prescribed one.
Is Rise safe?
When prescribed appropriately after screening, Rise is designed to be well tolerated. Common side effects include nausea, dizziness, flushing, headache, indigestion, nasal congestion, back pain, and muscle aches. These are usually mild and temporary. Because Rise combines multiple vasoactive agents, our intake screens rigorously for cardiac history, blood pressure, and interacting medications, and re-screens at every renewal.
Will anyone know?
No. Your assessment is private, your medication ships in plain unmarked packaging, your billing descriptor is discreet, and your health information is protected under HIPAA.
Does Rise qualify for HSA/FSA?
Yes. Use your HSA or FSA card at checkout. Contact your plan provider to confirm eligibility and reimbursement details.
Can I adjust or cancel my plan?
Anytime. Switch between 4 and 6 doses per month, step down to a single-agent option with your provider, pause, or cancel from your Shed portal. No fees, no long-term contracts.
Rise by Shed

Ready when you are. For up to 36 hours.*

Get started Prescription required · Free online visit · Cancel anytime · From $XX/mo
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Rise from $XX/mo Free visit · Rx required · Cancel anytime
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