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Semaglutide vs tirzepatide:
What’s the difference?

Both are powerful GLP-1-based medications, but they work slightly differently. Here’s how they compare, so you and your provider can find the best fit.

Semaglutide

Most popular
  • Same active ingredient as Ozempic®*
  • GLP-1 receptor agonist
  • Lose up to 15% of body weight*
  • Taken weekly

Tirzepatide

Most effective
  • Same active ingredient as Wegovy®*
  • Dual receptor agonist (inhibits GIP and GLP-1 receptors)
  • Lose up to 20% of body weight*
  • Taken weekly
*In clinical trials studying Wegovy® (2.4 mg), the average weight loss was 15% and 20%, respectively, when paired with diet and exercise (compared to 2.4% and 3.1% with diet and exercise alone). Results may vary. Compounded medications are not FDA-approved and are made by a licensed pharmacy based on a provider’s prescription.

Real results from Shed members

Before
After
Bjorn
“The journey is tough and challenging, but fruitful. Knowing your body's capability and constantly challenging yourself I find is the key. Consistency is the key.”

Your simple, 4-step wellness plan

Step 1

Complete form

Fill out a 5-minute form about your health history and which admin method you prefer.
Step 2

Get your prescription

A medical provider will look over your answers and determine if you’re a good fit—no appointment required.
Step 3

Medications shipped to your home

Your prescription will be discreetly delivered right to your doorstep.
Step 4

Ongoing support

Health coaching, unlimited provider appointments, health courses, and access to our collaborative community.  

Your simple, 4-step wellness plan

Step 1

Complete form

Fill out a 5-minute form about your health history and which admin method you prefer.
Step 2

Get your prescription

A medical provider will look over your answers and determine if you’re a good fit—no appointment required.
Step 3

Medications shipped to your home

Your prescription will be discreetly delivered right to your doorstep.
Step 4

Ongoing support

Health coaching, unlimited provider appointments, health courses, and access to our collaborative community.  

Start your personalized weight-loss journey today

It only takes a few minutes to see if you qualify—no insurance needed.