Do I need to take a GLP-1 medication forever?

June 7, 2025
5 minutes

If you’ve recently started a GLP-1 medication, you’re likely asking the same question so many others do: “How long do I need to be on this?”

It’s a fair and important question. But the answer isn’t as simple as a specific timeline. It depends on several key factors: your goals, your lifestyle habits, your body’s response, and most of all, your mindset about what these medications are.

Let’s unpack it.

GLP-1s are a tool, not a magic switch

GLP-1 medications are incredibly effective at reducing appetite, improving blood sugar regulation, and helping the body respond better to insulin. For many, they’ve unlocked progress that felt out of reach for years. But they’re not magic. They don’t fix metabolism or mindset, and they don’t teach sustainable habits on their own.

Think of GLP-1s like training wheels. They help stabilize the ride while you strengthen the skills you need to ride solo. If you build a lifestyle while using them—eating in a way that supports your metabolism, moving your body consistently, managing stress, and sleeping well—you’re far more likely to sustain results if or when you choose to taper off.

Why many people regain weight after stopping

Here’s the reality: studies show that when people stop taking GLP-1 medications, weight regain is common, especially if lifestyle changes weren’t solidified along the way.

This isn’t a failure of willpower. It’s the body doing what it’s designed to do: protect you from starvation by increasing hunger signals and slowing metabolism. GLP-1s help override that drive, but once the medication is gone, your physiology returns to baseline unless something else has changed.

The “something else” is your lifestyle.

So, how long should you take it?

There’s no one-size-fits-all answer. Some people stay on GLP-1s for years, especially if they have chronic conditions like type 2 diabetes or PCOS. Others use them as a shorter-term catalyst to build new habits and then transition off with a strong foundation in place.

Here’s what to consider:

  • What’s your long-term goal? If it’s sustainable weight maintenance, focus on building habits now that you can keep for life.

  • Are you drinking water or eating enough protein, fiber, and whole foods? These stabilize blood sugar and support satiety even without a GLP-1; these should be a lifelong practice, not a temporary tool for active weight loss.

  • Are you moving regularly, especially with strength training? Muscle is your metabolic ally.

  • Do you understand your hunger cues? GLP-1s can blunt them, but intuitive eating skills matter once they’re gone.

  • Are you working with a provider or coach to create a maintenance plan? Transitioning off doesn’t have to mean going it alone.

The bottom line

GLP-1s aren’t forever for everyone. But how long you stay on one should be a strategic decision based on your individual needs, not fear, guilt, or pressure. The real question isn’t just how long you’ll take the medication, but what you do while you’re on it.

If you’re using this tool to build the mindset, structure, and confidence needed to live well without it someday, you’re on the right path. And if staying on a low dose long-term helps you maintain health without harm? That’s okay too.

What matters most is that your approach is informed, intentional, and aligned with the life you want to live.

At Shed, we help you answer the question: “Are you working with a provider or coach to create a maintenance plan for inevitable success?” 

Our lifestyle education, nutrition plans, and coaching are designed to make health sustainable. We empower you to become the real you—confident, capable, and in control of your long-term success.

Written by: Kory Morse, M.S., Head of Member Education at Shed

Kory is a certified holistic health and life coach with a Master of Science in Integrative and Functional Nutrition, specializing in research, biochemistry, and systems biology. As Head of Education at Shed and a member of the supplement research team, she blends scientific expertise with a compassionate, curiosity-driven approach to support lasting, sustainable change. Her mission is to make health feel accessible, empowering, and deeply personal.

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