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What is Foundayo® and how does it work?

Foundayo® (orforglipron) is a once-daily oral GLP-1 receptor agonist approved by the FDA for chronic weight management in eligible adults. It works by activating GLP-1 receptors involved in appetite regulation, helping reduce hunger and food intake. When combined with a reduced-calorie diet and increased physical activity, it can help people lose weight and maintain weight loss over time.

How is Foundayo® different from injectable GLP-1s?

Foundayo® is taken as a daily pill rather than an injection. It can be taken any time of day, with or without food, and does not have the food or water restrictions required by some other oral GLP-1 medications. Like other GLP-1 treatments, it works by targeting receptors involved in appetite regulation.

How do I take Foundayo®?

Foundayo® is taken by mouth once daily, with or without food. Swallow the tablet whole; do not crush, chew, or break it. Follow your healthcare provider’s instructions for your prescribed dose, including any dose increases over time.
Weight loss
Foundayo®
(orforglipron)

Foundayo® is a needle-free, FDA-approved GLP-1 pill with an average of 12.4%† body-weight loss. If prescribed, Foundayo® is shipped directly to your door in just a few days.

FDA-approved oral GLP-1
100% online, provider-led care
Shipped straight to your door
FSA/HSA eligible*
Foundayo® medication
Once-daily tablet
Starting at
$149 /month
Plus an additional $125/month Shed Membership. Medication pricing is for new patients using cash pay and is paid separately to the dispensing pharmacy.

What is Foundayo® and how does it work?

Foundayo® (orforglipron) is a once-daily oral GLP-1 receptor agonist approved by the FDA for chronic weight management in eligible adults. It works by activating GLP-1 receptors involved in appetite regulation, helping reduce hunger and food intake. When combined with a reduced-calorie diet and increased physical activity, it can help people lose weight and maintain weight loss over time.

How is Foundayo® different from injectable GLP-1s?

Foundayo® is taken as a daily pill rather than an injection. It can be taken any time of day, with or without food, and does not have the food or water restrictions required by some other oral GLP-1 medications. Like other GLP-1 treatments, it works by targeting receptors involved in appetite regulation.

How do I take Foundayo®?

Foundayo® is taken by mouth once daily, with or without food. Swallow the tablet whole; do not crush, chew, or break it. Follow your healthcare provider’s instructions for your prescribed dose, including any dose increases over time.
U.S.-LICENSED PROVIDERS
150K+ MEMBERS
PROVIDER-PRESCRIBED
PERSONALIZED PLANS
SHIPPED TO YOUR DOOR
FSA/HSA ELIGIBLE*
ONCE-DAILY PILL
100% ONLINE
NO NEEDLES
U.S.-LICENSED PROVIDERS
150K+ MEMBERS
PROVIDER-PRESCRIBED
PERSONALIZED PLANS
SHIPPED TO YOUR DOOR
FSA/HSA ELIGIBLE*
ONCE-DAILY PILL
100% ONLINE
NO NEEDLES
U.S.-LICENSED PROVIDERS
150K+ MEMBERS
PROVIDER-PRESCRIBED
PERSONALIZED PLANS
SHIPPED TO YOUR DOOR
FSA/HSA ELIGIBLE*
ONCE-DAILY PILL
100% ONLINE
NO NEEDLES
GLP-1 Weight loss, minus the needle.

Weight-loss treatment doesn’t have to involve injections. Oral options offer another way to approach medical weight management, without adding a weekly shot to your routine.

About 2 minutes • 100% online • Cancel anytime
Foundayo® may be right for you if:
Hunger keeps getting in the way
Foundayo® works on GLP-1 receptors involved in appetite regulation, helping reduce hunger and food intake.
You want a proven, FDA-approved option
Foundayo® is FDA-approved for chronic weight management. In the ATTAIN-1 clinical trial, participants taking the highest dose lost an average of 12.4% of their body weight over 72 weeks.
You want to skip the needles
Get GLP-1 treatment in a once-daily pill instead of an injection.
You want a simple daily routine
Take one pill daily, with or without food, at any time of day.
You want extra support along the way
Foundayo® was studied alongside a reduced-calorie diet and increased physical activity. With Shed, you also get access to nutrition coaching to help you build healthy habits and work toward your goals.
You want a medically guided approach
A licensed provider reviews your information to determine whether treatment is appropriate for you.
150,000+ Shed members.
Real weight-loss results.

Across all Shed programs, members have seen what's possible with the right medication, personalized care, and ongoing support.

Before
After
-60
lbs
Kim H.
Verified Member
Before
After
-53
lbs
Alyssa K.
Verified Member
Before
After
-80
lbs
Bryanna M.
Verified Member
Before
After
-30
lbs
Sue P.
Verified Member
Before
After
-53
lbs
Dawn
Verified Member
Before
After
-31
lbs
Michelle H.
Verified Member
Before
After
-50
lbs
Carolann
Verified Member
Before
After
-77
lbs
Michelle C.
Verified Member
Before
After
-60
lbs
Al S.
Verified Member
Before
After
-30
lbs
Jessica A.
Verified Member
Before
After
-70
lbs
Jesse E.
Verified Member
Before
After
-59
lbs
Lisa P.
Verified Member
Shed members across all programs
MEMBERS
150,000+
POUNDS LOST
1.25M+
AVERAGE WEIGHT LOSS
9.8%*

About 2 minutes • 100% online • No appointment required

Figures are based on self-reported data. Percentages of average weight loss are from VIP member data, while total pounds lost reflect self-reported data from all members. Results may vary. Some states may require virtual appointment.

Foundayo® works best alongside healthy habits. Your Shed membership gives you the support to build them.
Your $125/month Shed Membership covers your provider-led care and support. Medication is not included and is paid separately to the dispensing pharmacy.
Unlimited provider visits and follow-ups
Support from our Member Success and medical teams every step of the way
Dedicated support on prescription orders
Expert-crafted nutrition plans built around how you eat
Plan adjustments whenever you need them
Every prescription, message, and update in one login
How Foundayo® works
Orforglipron: The science-backed ingredient in Foundayo®

Orforglipron is the active ingredient in Foundayo®, an FDA-approved, once-daily oral GLP-1 receptor agonist. It works by activating GLP-1 receptors involved in appetite regulation, helping reduce food intake and support weight management.

Targets appetite regulation

Activates GLP-1 receptors that play a role in hunger and food intake.

Helps reduce food intake

Works on pathways involved in appetite, helping you feel satisfied with less food.

Designed for daily use

A once-daily pill that can be taken at any time of day, with or without food. No injections needed.

Weight loss support backed by clinical research.
The science behind hunger, appetite, and weight loss

GLP-1 is a hormone that helps regulate appetite and food intake. Foundayo® (orforglipron) is a GLP-1 receptor agonist taken by mouth, made to support appetite control, reduced cravings, and healthy metabolic function.

Appetite control
Reduced cravings
Healthy metabolic function
Clinically studied, easy to use
12.4%
Average body-weight loss in the ATTAIN-1 clinical trial†
Highest dose, participants who completed 72 weeks, with a reduced-calorie diet and increased physical activity, vs 0.9% with placebo.
About 2 minutes • Reviewed by a licensed provider
See what starting now could mean for your weight

Enter your current weight to see what different percentages of body-weight loss could mean in pounds.

About 2 minutes • 100% online
Your Current Weight
220 lbs

Potential Equivalents at 220 lbs

Tap a scenario to chart it

At 10% loss

22 lbs

At 15% loss

33 lbs

At 20% loss

44 lbs

IF YOU LOST 20% - OVER 18 MONTHS

240 220 200 180 160 176 lbs
Now 3mo 6mo 9mo 12mo 15mo 18mo

Losing 20% of 220 lbs would be 44 lbs down, putting you at 176 lbs. At the pace shown above, about 26 lbs of that would come in the first 6 months.

For illustration only. This shows what a 10%, 15%, or 20% loss from your current weight would add up to, and one example of a pace it could follow. It is not a prediction of your results, not a promise that you will lose any amount of weight, and not medical advice.

100% online. 100% on your schedule
Step 1
Complete form

Answer a few questions about your health history and goals.

Step 2
Provider review

A licensed medical provider reviews your answers and determines if Foundayo® is a good fit for you.

Step 3
Shipped to your home

If prescribed, your medication is filled by a third-party dispensing pharmacy and delivered with clear instructions.

Step 4
Ongoing support

Unlimited provider follow-ups and support from your Member Success Team.

WHAT TO EXPECT
What your first 6 months could look like

Everyone responds differently, but Foundayo® is typically introduced gradually while your provider monitors your progress and adjusts your treatment plan as needed.

Real patients feel steady progress, not overnight change.
Week 1
Start your treatment
Get started with a personalized treatment plan designed around your needs, with support from your provider and Health Coach.
Your Shed support
Unlimited provider follow-ups
Health Coaching and nutrition plan
Guidance on taking your medication
Weeks 2–4
Build a healthy routine
Make your medication part of your routine and build the habits that support your goals.
Focus
Take your medication as prescribed
Build sustainable, balanced eating habits
Stay active with consistent exercise
Get support from your Health Coach, Provider and Care Team
Months 2–3
Start noticing the difference
For many patients, this is when weight-loss progress may become more noticeable*. You may start seeing the pounds come off, noticing changes on the scale, and feeling a difference in how you feel day to day.
What may change
Track the pounds lost and progress made
Stay consistent with your medication and healthy habits
Work with your provider to personalize your plan as needed
Months 4–6
See how far you’ve come
As you continue making progress, you may notice bigger changes in your body, the way your clothes fit, and how confident you feel. Keep building on your progress and working with your team to reach your weight-loss goals.
Your plan comes with real support.
Your Shed care team stays with you throughout treatment, from your first dose through ongoing adjustments and support.
About 2 minutes · 100% online · No appointment required
Dr. Asad Niazi
MD, MPH
Dr. Abhi Patel
DO
Neely Wood
RN
Kristin Olson
DNP
YOUR SHED CARE TEAM
A provider-led team focused on your progress.

Your Shed program connects you with professionals who can support different parts of your weight-loss journey.

Licensed medical provider
Reviews your health information, determines whether treatment is appropriate, and manages your prescribed medication.
Member Success
Helps you navigate the Shed experience and get the support you need throughout your membership.
Health Coach
Supports the habits, routines, and lifestyle changes that can help you stay consistent.
Registered dietitian resources
Nutrition guidance designed to help you build healthier eating habits alongside treatment.
Medication starts the change. Your care team keeps your plan working for you.
About 2 minutes • Reviewed by a licensed provider
CARE YOU CAN TRUST
Safe, licensed medical care from start to finish

Shed connects eligible members with licensed medical providers and trusted pharmacy partners through a secure online treatment experience.

Licensed Medical Providers
Your treatment is reviewed and managed by a licensed provider.
U.S. Pharmacy Partners
Prescribed medication is fulfilled through qualified pharmacy partners.
Secure Online Care
Your health information is handled through a secure telehealth experience.
Ongoing Clinical Support
Your care does not stop after your first prescription.
HSA/FSA Eligible*
Eligible members may be able to use HSA or FSA funds for treatment.
No Insurance Required
Access treatment without navigating traditional insurance approval.
SHED FAQs
Questions? Answers.

What is Shed?

Shed is a telehealth clinic that connects you with licensed providers for personalized, prescription-based care. Your membership includes provider-led care, follow-ups, and support from our Member Success Team to help you navigate your treatment.

What kind of results can I expect on Foundayo®?

In the ATTAIN-1 clinical trial, participants taking the highest dose who completed 72 weeks of treatment lost an average of 12.4% of their body weight, compared with 0.9% with placebo. Results were seen alongside a reduced-calorie diet and increased physical activity. Individual results vary, and weight loss is not guaranteed.

How is Foundayo® different from injectable GLP-1s?

Foundayo® is taken as a daily pill rather than an injection. It can be taken any time of day, with or without food, and does not have the food or water restrictions required by some other oral GLP-1 medications. Like other GLP-1 treatments, it works by targeting receptors involved in appetite regulation.

How do I take Foundayo®?

Foundayo® is taken by mouth once daily, with or without food. Swallow the tablet whole; do not crush, chew, or break it. Follow your healthcare provider’s instructions for your prescribed dose, including any dose increases over time.

Are there any side effects of Foundayo®?

Common side effects include nausea, constipation, diarrhea, vomiting, indigestion, abdominal pain, headache, fatigue, bloating, belching, heartburn, gas, and hair loss. Foundayo® also carries a boxed warning about the risk of thyroid C-cell tumors observed in animal studies. It should not be used by people with a personal or family history of medullary thyroid carcinoma (MTC) or people with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Talk with your provider about the full risks and benefits before starting treatment.

Is Foundayo® right for everyone?

No. Foundayo® is FDA-approved for chronic weight management in adults with obesity or adults who are overweight and have at least one weight-related health condition. A licensed provider will review your medical history, current medications, and health goals to determine whether it's appropriate for you. It is not suitable for everyone.

Does Foundayo® need to be refrigerated?

No. Foundayo® can be stored at room temperature, between 68°F and 77°F. Keep it in its original bottle and carton to protect it from light, and keep all medication out of reach of children.

How much does it cost?

Foundayo® through Shed starts at $149 per month for the medication, plus a $125 monthly Shed membership fee. The membership includes provider-led care and ongoing support. Medication costs are paid separately to the dispensing pharmacy, and your final cost may vary based on your prescribed dose and eligibility for savings programs.

†Weight loss results based on ATTAIN-1 Phase 3 clinical trial data for participants taking the highest dose who completed 72 weeks of treatment with a reduced-calorie diet and increased physical activity. Source: Foundayo Prescribing Information. Lilly USA, LLC, 2026. *Shed member statistics reflect members across all Shed programs and are not specific to Foundayo®. 9.8% average weight loss is from self-reported Shed member data, and total pounds lost reflects self-reported data from all members. Member photos show Shed members across all programs. Foundayo® pricing starts at $149/month for new patients using cash pay. Price does not include the $125 Shed membership and provider fee, paid directly to Shed. Medication costs are paid separately to the dispensing pharmacy. Foundayo® is FDA-approved for chronic weight management in adults with obesity or overweight with at least one weight-related condition. Results vary by individual and are not guaranteed. Weight loss depends on factors such as diet, exercise, adherence, medical history, and individual response. Providers may evaluate patients and prescribe Foundayo® when clinically appropriate. Prescriptions are based on a medical evaluation and are at the provider's discretion. Shed is not a pharmacy and does not dispense medications. Prescriptions are fulfilled and shipped by a third-party dispensing pharmacy. Medications carry risks and side effects. Patients should review the full Prescribing Information and Medication Guide and discuss risks with their provider. Foundayo® may cause tumors in the thyroid, including thyroid cancer. Do not use if you or any family member has had medullary thyroid carcinoma (MTC), or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Common side effects include nausea, constipation, diarrhea, vomiting, indigestion, stomach pain, headache, and fatigue. Foundayo® may reduce the effectiveness of oral birth control pills, and providers may recommend alternative contraception for 30 days after starting and after each dose increase. This is not a complete list of side effects. See full Prescribing Information at foundayo.lilly.com. Foundayo® is a registered trademark of Eli Lilly and Company. Shed is not affiliated with or endorsed by Eli Lilly and Company.

*FSA/HSA eligibility depends on your individual plan. Please check with your plan administrator to confirm coverage before using your FSA/HSA card.