Does semaglutide make you look older? Tips to protect skin appearance while losing weight

August 14, 2025
5 minutes
Author:
Angie Carter, Health Writer at Shed

When losing weight, your primary focus is likely on shedding those extra pounds. But you might be worried about the potential impact it will have on your skin, too. You've probably heard whispers or read online about how weight loss, especially with medications like semaglutide, might make you look older. Perhaps you've even noticed changes in your skin or overall appearance as the number on the scale drops. But don’t worry—with the right strategies, you can minimize the impact that weight loss will have on your skin.

In this article, we’ll explore whether semaglutide really makes you look older, explore the connection between weight loss and aging, and provide practical tips to help you support your skin’s appearance as you lose weight.

Does semaglutide make you look older?

Semaglutide, a GLP-1 receptor agonist, is an effective weight-loss medication that has helped many people achieve a healthier weight. However, some are deterred from considering semaglutide for weight loss because of the risk of the dreaded “Ozempic face,” which makes the face look hollow or gaunt. This is why it’s important to distinguish between the effects of weight loss itself and the specific effects of semaglutide.

Semaglutide mimics the hormone GLP-1, which helps regulate appetite and blood sugar levels. This can lead to reduced food intake and weight loss. Losing a significant amount of weight can lead to changes in your skin’s appearance due to the loss of fat underneath the skin. This fat loss can result in sagging or loose skin, which might give the impression of an aged appearance. However, semaglutide itself does not directly cause aging of the skin.

What’s crucial to understand is that “looking older” after weight loss is more about how quickly you lose weight rather than the method itself. With proper care, you can mitigate the impact weight loss has on your skin.

Weight loss and aging: What’s the connection?

Weight loss, especially when it's rapid or significant, can have noticeable effects on your appearance. While losing weight is beneficial for overall health, it can sometimes make you look older due to several factors.

  • Loss of subcutaneous fat: Subcutaneous fat is the layer of fat just beneath your skin that gives your face a youthful plumpness. When you lose a lot of weight, this fat layer decreases, leading to a hollow or sunken appearance in the face. This can make fine lines and wrinkles more noticeable, contributing to an aged look.
  • Skin elasticity and sagging: The skin’s ability to bounce back after weight loss depends largely on its elasticity. Younger skin tends to be more elastic and can recover more easily after weight loss. However, as you age, your skin naturally loses elasticity due to decreased collagen and elastin production. When you lose weight in a short amount of time, the skin may not be able to tighten up quickly enough, leading to sagging or loose skin.
  • Muscle loss: Weight loss can sometimes lead to muscle loss, especially if you're not doing resistance training or consuming enough protein. Muscle mass contributes to the fullness and tone of your face and body. As muscle decreases, the skin may appear less firm, and the loss of this underlying structure can contribute to an older appearance.
  • Dehydration and dull skin: Dehydration is another factor that can make your skin look dull and less vibrant. As you lose weight, especially if you’re not drinking enough water, your skin may become dehydrated, leading to a lackluster appearance. Hydrated skin is plumper and more resilient, which contributes to a youthful look.

Tips for protecting skin during weight loss

Stay hydrated

One of the simplest and most effective ways to keep your skin looking youthful during weight loss is to stay hydrated. Drinking plenty of water helps to maintain skin elasticity, reduces the appearance of fine lines and wrinkles, and keeps your skin looking plump and vibrant. Aim to drink at least eight glasses of water a day, and consider adding hydrating foods to your diet, such as cucumbers, watermelon, and oranges, or a supplement like Clear Protein Hydration.

Support collagen production

Collagen is a key protein that helps keep your skin firm and elastic. As you age, your body produces less collagen, which can lead to sagging skin. To support collagen production during weight loss, consider taking a collagen supplement or incorporating foods that are rich in vitamin C and amino acids, such as citrus fruits, berries, and leafy greens. 

Practice good skincare

A consistent skincare routine is essential in protecting your skin’s health and appearance during weight loss. Use a gentle cleanser to remove impurities without stripping your skin’s natural oils, followed by a moisturizer that suits your skin type to lock in hydration. Incorporate products with ingredients like hyaluronic acid, which helps retain moisture, and antioxidants like vitamin C, which protect against environmental damage. Regular exfoliation can also help to remove dead skin cells and promote cell turnover, leading to a brighter complexion.

Avoid rapid weight loss

While it can be tempting to lose weight quickly, rapid weight loss can exacerbate the appearance of aging. A slow and steady approach is more sustainable and allows your skin time to adjust to the changes in your body. Aim to lose no more than 1-2 pounds per week. Medications like semaglutide and tirzepatide, available through Shed, can help facilitate steady, controlled weight loss, ensuring that your body has time to adapt.

Engage in strength training

Strength training is crucial in maintaining muscle mass during weight loss. Building and preserving muscle can help keep your skin looking firm and youthful. Incorporate resistance exercises like weight lifting, bodyweight exercises, or resistance band workouts into your fitness routine at least two to three times a week. Maintaining muscle mass not only enhances your overall appearance but also supports a higher metabolism, which is beneficial for long-term weight management.

Focus on a balanced diet

A well-balanced diet is key to maintaining healthy, youthful skin during weight loss. Make sure you're getting enough protein, which is essential for muscle maintenance and skin health. Foods rich in healthy fats, such as avocados, nuts, and olive oil, provide the essential fatty acids that help keep your skin soft and supple. Incorporating a variety of fruits and vegetables will supply your body with the vitamins and antioxidants it needs to fight off the signs of aging and promote skin health.

Protect your skin from the sun

Sun exposure is one of the leading causes of premature aging. Whether you’re losing weight or not, it’s important to protect your skin from harmful UV rays by applying sunscreen daily. Choose a broad-spectrum sunscreen with an SPF of at least 30, and reapply every two hours when spending extended periods outdoors. Wearing protective clothing, such as hats and long sleeves, can also help minimize sun damage.

Get enough sleep

Sleep is crucial for overall health and plays a significant role in how your skin looks. During sleep, your body repairs and regenerates cells, including skin cells. Aim for 7–9 hours of quality sleep each night to allow your skin to recover and maintain a youthful glow. Poor sleep can lead to dark circles, a dull complexion, and an overall tired appearance, which can detract from the youthful look you're striving to maintain during weight loss.

Manage stress

Chronic stress can damage your skin, leading to breakouts, dullness, and accelerated aging. While you may not be able to eliminate stress from your life, managing it is essential for maintaining a youthful appearance. Consider practices such as yoga, meditation, deep breathing exercises, or spending time in nature to help reduce stress levels. A calm mind often reflects in healthy, glowing skin.

Incorporate antioxidants

Antioxidants protect your skin from oxidative stress, which can accelerate aging. Eating antioxidant-rich foods such as berries, dark chocolate, spinach, and green tea regularly can help combat free radical damage and promote a youthful complexion. Antioxidants can also be found in many skincare products, providing additional protection when applied topically.

Losing weight, especially with the help of medications like semaglutide, can bring about significant changes to your body and appearance. If you’re worried about trading pounds for an aged appearance, following these tips can help you maintain a youthful, vibrant look. Whether you're taking semaglutide or another approach to weight loss, remember that a healthy, gradual approach is key to achieving lasting results without compromising your youthful glow.

FAQs

Does semaglutide make you look older?

Some people worry that taking semaglutide will make them look older. However, the medication itself does not age your skin. Rather, rapid weight loss can lead to loss of subcutaneous fat in the face, making the skin look saggy or hollow.

What is “Ozempic face”?

Ozempic face refers to facial sagging, hollowing, or a gaunt look that can occur after someone loses weight quickly, often from a GLP-1 weight-loss medication like Ozempic. This occurs because of rapid weight loss, not the medication itself.

How do I prevent my skin looking older as I lose weight?

To prevent the appearance of skin aging during weight loss, aim to lose weight slowly (1–2 pounds per week) so your skin has time to adjust to the fat loss. A consistent skincare routine, sun protection, regular strength training (2–3 times per week), and an antioxidant-rich diet can also support youthful-looking skin.

What are the best skincare habits to incorporate during semaglutide weight loss?

If you’re taking a GLP-1, focus on habits that will support skin elasticity and collagen production. This includes drinking lots of water, wearing sunscreen daily, using skincare products with hyaluronic acid and peptides, taking a collagen supplement, and eating foods high in vitamin C.

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