STEP 01Spray.
One spray in each nostril, as your provider directs. No water and no pill.
BLACK FRIDAY $100 OFF your first month of ROXUS® with code ROXUS100
BLACK FRIDAY $100 OFF your first month of ROXUS® with code ROXUS100
ROXUS® is a prescription vardenafil nasal spray that absorbs through the lining of your nose, not your stomach. In published clinical studies, peak blood levels came in as little as 5 minutes, with a median of about 10 minutes.* Through Cyber Monday, take $100 off your first month.
New patients. Code applied at checkout. Prescribed by a licensed U.S. provider. If your provider doesn't approve treatment, you get a refund.
Fastest time to peak blood levels in studies1 2
Median time to peak blood levels in studies1 2
Vardenafil prescribed by doctors for over 20 years3
Published clinical research on intranasal vardenafil1 2
Review your health history before prescribing
ROXUS® is a prescription nasal spray made with vardenafil, a PDE5 inhibitor. That's the same proven class of ED medication doctors have prescribed for over 20 years,3 delivered a smarter way.
Most ED pills make you wait on your stomach, then your liver, and hope dinner didn't slow it all down. ROXUS® skips that route. And it's not hype: it has been studied in published clinical research.1 2
See if I qualify for $100 offSimplified. PDE5 inhibitors like vardenafil support the body's natural erection response by blocking the PDE5 enzyme, which lets cGMP stay active and helps blood flow. They work with sexual stimulation, not in place of it.
The inside of your nose is lined with tiny blood vessels. ROXUS® is designed to use that direct route into the bloodstream.
STEP 01One spray in each nostril, as your provider directs. No water and no pill.
STEP 02The inside of your nose is packed with tiny blood vessels, so ROXUS® absorbs straight through that lining and into your bloodstream.
STEP 03There's no stomach and no first pass through the liver. In clinical studies, peak blood levels came in as little as 5 minutes, median about 10 minutes.*
Instead of passing through the digestive system, the spray is absorbed across the nasal lining and into the small blood vessels just beneath it.
*Measures blood levels, not time to erection. Results vary.
Concept view of reported peak timing1 2
Illustrative only, not study data. Curve shapes and heights are conceptual. Only the timing markers reflect published values: as little as 5 minutes and median about 10 minutes for intranasal vardenafil vs. about 45 to 58 minutes for oral vardenafil.*
Same proven medication class. A different route in.
*In intranasal vardenafil studies, time to peak blood levels ranged from 5 to 120 minutes, median about 10. Pill timing refers to oral vardenafil.1 2 Measures blood levels, not time to erection. Results vary.
Switch for $100 offA clinically studied prescription medication, prescribed by a licensed provider and made by a licensed pharmacy.
Published in The Journal of Sexual Medicine and the European Journal of Pharmaceutical Sciences.1 2
Pharmacokinetic studies of intranasal vardenafil.Vardenafil has been prescribed for ED for over 20 years.3
Oral vardenafil was first approved by the FDA in 2003. ROXUS® itself is not FDA-approved.A licensed U.S. provider reviews every patient before prescribing.
If your provider doesn't approve treatment, you get a refund.Compounded by a licensed 503A pharmacy and tested for quality and sterility.
FDA registration of the pharmacy does not mean the medication is FDA-approved.Urologists and men's health clinicians on why the delivery route matters.
ROXUS® is changing what men can expect from ED treatment. It's fast, innovative, and fundamentally different from the traditional options men have relied on for years.
Trained at Harvard Medical School, Cleveland Clinic and UCLA. Contributor to SMSNA clinical guidelines.
The delivery route matters. ROXUS® takes a different approach from traditional oral ED medications, using intranasal delivery designed to work closer to the moment it's needed.
Fellowship-trained in male sexual and hormonal health. Former Director of the Men's Health Program at the University of Iowa. Board member, SMSNA.
ROXUS® is easy to use, responds quickly and there is no more worrying about when you last ate. Game changer in my clinical toolbox.
Over two decades in men's sexual health. Member of the Movember Sexual Health and Wellbeing Advisory Group.
Expert quotes reflect the individuals' own opinions. They were not compensated for their statements and are not Shed providers.
ED can really make you get in your head, and it was starting to affect my sex life. Now I feel like myself again. My wife is definitely happy about it too 😂.
I used to have to ask my girlfriend if she thought we'd be having sex that night so I'd know when to take my pill. I hated it. Now we don't have to plan around it like that.
I'll admit, I was skeptical at first. I didn't think a nasal spray would work that fast, but I started noticing the effects pretty soon after taking it. This has been a game changer for my sex life.
Testimonials are from verified ROXUS® patients and reflect their individual experiences. Individual results vary.
The questions men ask most about ROXUS® and the Black Friday offer. For anything specific to your health, your provider can help.
Claim $100 offP.S. The $100 off ends Cyber Monday at 11:59 PM ET. This isn't a gas station pill. It's a clinically studied medication prescribed by a real provider. And if your provider doesn't approve treatment, you get a refund.
*In clinical studies, time to peak blood levels ranged from 5 to 120 minutes, with a median of about 10 minutes. This measures blood levels, not time to erection. Individual results vary.
*Based on intranasal vardenafil studies: median time to peak blood levels about 10 minutes (range 5-120), vs. about 45-58 minutes for oral vardenafil. Measures blood levels, not time to erection. Results vary. ROXUS® is a prescription-only compounded medication and is not FDA-approved. Compounded drugs are not reviewed by the FDA for safety, effectiveness, or quality. Pharmacy FDA registration does not mean FDA approval of the medication. Expert quotes reflect the individuals' own opinions; they were not compensated for their statements and are not Shed providers. Don't use with nitrates (including poppers) or riociguat. Get medical help for an erection lasting over 4 hours, or for sudden vision or hearing loss. Side effects may include nasal congestion, headache, and flushing. ROXUS® is a registered trademark of LTR Pharma Ltd.
1Wang J, et al. J Sex Med. 2023;20(7):1004-1009.
2Chung E, et al. Eur J Pharm Sci. 2025;213:107226.
3Oral vardenafil was first approved by the FDA in 2003; ROXUS® is a compounded intranasal form and is not FDA-approved.
Black Friday offer: $100 off the first month of a new ROXUS® prescription with code ROXUS100. New patients only. Valid through Monday, November 30, 2026 at 11:59 PM ET. Requires an online assessment and a prescription from a licensed provider; the offer does not guarantee a prescription. Cannot be combined with other offers. No cash value.
Fig. 3 is an illustrative concept, not study data. Testimonials are from verified ROXUS® patients and reflect their individual experiences. Individual results vary. If your provider doesn't approve treatment, you get a refund.
ROXUS® is available by prescription only, after a licensed provider determines it's appropriate for you. Do not use ROXUS® if you take nitrates (including poppers) or riociguat; these combinations can cause a dangerous drop in blood pressure. Seek immediate medical attention for an erection lasting longer than 4 hours, or for sudden vision or hearing loss. Tell your provider about any heart conditions, recent heart attack or stroke, low blood pressure, or other medications you take. The most common side effects include nasal congestion, headache, and flushing. Use only as directed by your provider and do not exceed your prescribed dose.