Because Microdosing GLP-1 uses a lower dose of Semaglutide, it may be associated with a lower likelihood and severity of side effects compared to standard doses. Possible side effects are expected to be similar to other Semaglutide medications and can include nausea, diarrhea, constipation, abdominal pain, headache, and fatigue. Most side effects are temporary and may resolve within a few days to a few weeks—if they persist or worsen, contact your provider.